Expiration date: 01/2023

Release form and composition:

Tablets coated with a brown color, round, biconvex.

1 tablet contains:

dry water extract of fresh artichoke leaves 200 mg

Excipients: magnesium trisilicate, corn starch, talc, magnesium stearate.

Shell composition: gummilac, rosin, talc, gelatin, acacia gum, sucrose, calcium carbonate, Carnauba wax, polysorbate 80, dispersed dye (sucrose, iron oxides yellow, black and brown (E172), methyl parahydroxybenzoate (E218), ethyl parahydroxybenzoate (E214)).

12 pcs. - blisters (5) - packs of cardboard.

30 pcs. - blisters (2) - packs of cardboard.

30 pcs. - blisters (6) - cardboard packs.

180 pcs. - polypropylene tubes (1) - cardboard bundles.

The solution for oral administration is dark brown, opaque, with a slight yellowish precipitate, there may be a small precipitate during storage.

1 ml contains:

thick water extract of fresh artichoke leaves 200 mg

Excipients: ethanol, orange flavor, glycerol, methylparahydroxybenzoate, propylparahydroxybenzoate, purified water.

120 ml-dark glass bottles (1) - cardboard packs.

Pharmacological action:

The drug is of plant origin. The pharmacological effect of the drug is due to the complex of biologically active substances included in the leaves of artichoke field. Tsinarin in combination with phenolic acids has a choleretic and hepatoprotective effect. Ascorbic acid, carotene, vitamins B1 and B2, inulin contribute to the normalization of metabolic processes.

It also has a diuretic effect and increases the excretion of urea.


The effect of the drug Hofitol is the combined effect of its components, so it is not possible to conduct kinetic observations all together the components cannot be traced using markers or bioassays. For the same reason, it is impossible to detect the metabolites of the drug.


As part of complex therapy:

  • biliary dyskinesia by hypokinetic type
  • chronic non-calculous cholecystitis
  • chronic hepatitis
  • cirrhosis of the liver
  • chronic nephritis
  • chronic renal failure.

The dosage regimen:

Adults are prescribed 2-3 tab. or 2.5-5 ml of oral solution 3 times/day before meals. The course of treatment is 2-3 weeks.

Children older than 6 years, depending on the age, are prescribed 1-2 tab. 3 times/day before meals. The solution for oral administration, depending on age, is prescribed for 1/4-1/2 doses used in adults, 3 times/day before meals. The course of treatment is 2-3 weeks.

The need for repeated courses of therapy is determined individually by the doctor.

Side effects:

From the digestive system: it is possible to develop diarrhea with prolonged use of the drug in high doses.

Other: allergic reactions.


  • cholelithiasis
  • obstruction of the biliary tract
  • acute diseases of the liver, kidneys, bile and urinary tract
  • children under 6 years of age (for tablets)
  • hypersensitivity to the components of the drug.

Pregnancy and lactation:

There are reports that the use of Hofitol in the complex treatment of preeclampsia contributes to the improvement of the clinical course of the disease. Hofitol is used in a complex of preventive measures at the risk of developing gestosis from the early stages of pregnancy.

Data on the safety of the use of the drug Hofitol during lactation (breastfeeding) are not provided.

Special instructions:

With prolonged use of the drug in high doses, the risk of diarrhea increases.

1 teaspoon of oral solution contains 130 mg of ethyl alcohol.


Symptoms: perhaps the increasing incidence of side effects.

Drug interaction:

The drug interaction of the drug Hofitol is not described.

Storage conditions and terms:

The drug should be stored out of the reach of children at a temperature not exceeding 25°C. Shelf life of tablets - 3 years, solution for oral administration-4 years.