To drugs intermediante type includes substances that specifically interact with certain systems of mediators/modulators. Basically, they are agonists or antagonists of the respective receptors. Some of them mediated via endogenous ligands by changing their metabolism, release, capture and others.

Among intermediantes allocate drugs with preferential action on dopaminergic, serotonergic, adenosinergic and other systems.

• Agonists I1-imidazoline receptors
• Adenosinergic

• Angiotensin II receptor antagonist
• Histaminolytics

• Histaminomimetics
• Dopamine agonists

• Prostaglandins, thromboxanes, leukotrienes
• Serotonergic