Anabolism is the biosynthesis of metabolic products (proteins, fats, carbohydrates), as opposed to catabolism — the other component of the metabolic rate, which means the decay (degradation) products. Both processes in the body are implemented by enzymatic pathways (in most cases).
The anabolic effect of some steroidal and nonsteroidal compounds.
Of steroid substances have anabolic activity preparations of male sex hormones — androgens (see ANDROGEN, ANTIANDROGENS). However, their use as therapeutic anabolic prevent androgenic properties. In this regard, was synthesized compounds similar in structure to the androgens (steroids), but has a predominantly anabolic activity. They were called anabolic steroids.
The most characteristic property of the substances of this group is their ability to stimulate protein synthesis in the body and cause a decrease in the excretion of nitrogen (positive nitrogen balance). Reduces the allocation of the necessary for the synthesis of proteins, potassium, sulfur and phosphorus. Anabolic drugs promote the fixation of calcium in the bones. Clinically, the action of steroid anabolics is manifested in the increase of appetite, improvement of health, the General condition of patients, increasing body mass. This group of drugs accelerate calcification of the bones (osteoporosis). To achieve a pronounced effect concurrently with anabolic drugs patients should receive dietary adequate amounts of proteins, fats, carbohydrates, vitamins and minerals. Different drugs belonging to the group of steroid anabolics have different strength and duration of the anabolic effect and also differ according to the residual androgenic activity.