Immunoglobulins

Immunoglobulins are proteins of human (animals) who are carriers of the activity of antibodies present in blood, cerebrospinal fluid, lymph nodes, spleen, saliva and other tissues. They are synthesized in lymphoid cells contain carbohydrate groups and can be considered as glycoproteins. The electrophoretic mobility immunoglobulins relate mainly to gamma-globulin and beta2-globulins. The biological role of immunoglobulins in the body involves the processes of immunity. Their protective function is the ability to specifically interact with antigens.

Immunoglobulins (gamma globulins) is the purified and concentrated preparations of gamma-globulin fraction of serum proteins, contain high titers of antibodies. The release of ballast whey protein helps reduce toxicity and provides rapid response and strong bonding with antigens. The use of gamma globulin reduces the number of allergic reactions and complications arising from the introduction of heterologous sera. Modern technology is a human immunoglobulin guarantees the death of the virus of infectious hepatitis. The main immunoglobulin in preparations of gamma globulin is IgG. Serum and gamma-globulin is administered in the body in different ways: subcutaneously, intramuscularly, intravenously. It is also possible introduction into the spinal canal. Passive immunity occurs within hours, and lasts up to two weeks.

Homologous serum or gamma-globulins do not cause anaphylactic reactions and are once. Human gamma-globulin to prevent measles is administered intramuscularly in an amount of 1.5–3 ml.

An important condition for the effective use of serums and gamma globulins for the treatment and prevention of infectious diseases is the earliest appointment with the disease or infection.



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