• Triampur compositum (Hydrochlorothiazide + Triamterene) 50 tablets

Expiration date: 01/2024

Type and form of issue:

Tablets. 1 tablet contains:

active substance:

triamteren 25 mg

hydrochlorothiazide 12, 5 mg

excipients: lactose monohydrate-63 mg potato starch-20, 725 mg povidone K25-3, 9 mg silicon colloidal dioxide-0, 975 carboxymethyl starch sodium-2, 6 mg magnesium stearate-1, 3 mg

50 PCs. in bottles of colorless glass with a white cap made of LDPE with the embossed inscription " AWD " in a pack of cardboard 1 bottle.

Description of the dosage form:

Yellow, round, flat tablets with a risk on one side and with beveled edges, smooth surfaces, solid edges and the same appearance.

Indications:

Arterial hypertension, edematous syndrome of various Genesis (in chronic heart failure, liver and kidney diseases).

Maintenance therapy in the treatment of heart failure with glycosides in patients with a tendency to form edema.

Contraindications:

Hypersensitivity (including to sulfonamides), renal failure, anuria, acute glomerulonephritis, severe liver function disorders (precoma and hepatic coma), non-correctable electrolyte metabolism disorders: hypokalemia, hyperkalemia, hypercalcemia, hyponatremia hypovolemia.

Use during pregnancy and lactation:

Contraindicated during pregnancy. Breast-feeding should be stopped during treatment.

Side effect:

From the nervous system and sense organs: sometimes-ataxia, drowsiness, dry mouth, thirst, fatigue, headache, nervousness rarely-weakly expressed visual disorders, deterioration of existing myopia, reduced tear secretion, etc.

From the cardiovascular system and blood (hematopoiesis, hemostasis): sometimes-ECG changes, palpitations, lowering blood PRESSURE, orthostatic hypotension, changes in the blood picture, etc.

From the digestive tract: nausea, vomiting, diarrhea, sometimes — pain in the epigastrium, adinamia of the intestinal smooth muscle, partial intestinal obstruction in some cases — jaundice, hemorrhagic pancreatitis, inflammation of the gallbladder (in the presence of gallstone disease).

From the side of metabolism: violation of electrolyte balance, water metabolism, metabolic acidosis, increased cholesterol, triglycerides, glucose, uric acid in the blood dehydration, hypovolemia.

From the musculoskeletal system: lethargy of skeletal muscles, muscle tension, convulsions of the calf muscles.

Allergic reactions: in rare cases-redness and itching of the skin, urticaria, erythematosis, exanthema, fever.

Drug interaction:

Antihypertensive drugs (especially ACE inhibitors), diuretics, barbiturates, phenothiazines, tricyclic antidepressants, vasodilators enhance the hypotensive effect of NSAIDs — weaken.

Indomethacin with simultaneous use reduces glomerular filtration, colestyramine reduces absorption, potassium salts, potassium-sparing diuretics, ACE inhibitors increase the risk of hyperkalemia, glucocorticoids and laxatives — hypokalemia.

It weakens the action of antidiabetic, antiopodagric agents, noradrenaline and epinephrine, increases the cardio-and neurotoxic effect of lithium, side effects of salicylates on the Central nervous system increases the effect of curare-like muscle relaxants, cardiac glycosides (in the presence of potassium and/or magnesium deficiency in the body), cytostatics (on the bone marrow) reduces the excretion of quinidine.

Dosage and administration:

Inside, after eating, without chewing and drinking a small amount of water.

Edematous syndrome: the initial dose is determined by the severity of violations of water-electrolyte metabolism and is usually 1 table. 2 times a day after meals, then it is possible to increase the dose to the maximum daily dose (4 table.): 2 tables. after Breakfast and 2 tables. after dinner.

When compensating for edema, they switch to maintenance therapy for 1-2 tables. in 1-2 days.

Arterial hypertension: the initial dose is 1 tablespoon. per day (in the morning, after Breakfast), then the dose is gradually increased. The maximum daily dose is 4 tablets. In patients with impaired renal function (creatinine Cl-30-50 ml / min), the maximum daily dose is 1 table.

Triampur
compositum
(Hydrochlorothiazide
+
Triamterene)
50
tablets

  • $12.65