Belonging to this group, interact with n-cholinergic receptors located in autonomic ganglia (sympathetic and parasympathetic) and the so-called analogues of ganglionic tissue (sinocarotid zone and medulla of the adrenal glands). In addition, they have the ability to excite n-cholinergic receptors located in the CNS.

Main effects of drugs of this group are eucalyptus (through the n-cholinergic receptors sinocarotid zone) stimulation of the respiratory center (analeptic effect) and the increase in blood pressure as a result of interaction with n-cholinergic receptors of chromaffin tissue of the adrenal glands (increased adrenaline) and sympathetic ganglia (increased sympathetic impulses to heart and blood vessels).

With the advent of drugs more selective and pronounced hypertensive action, and the empowerment of resuscitation (artificial ventilation, etc.) called the effects of n-cholinomimetics has lost clinical significance. Now the main aspect of their application is reproduction n-cholinomimetic effects of nicotine. The use of these drugs helps to reduce the severity of withdrawal symptoms when quitting Smoking.

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