• Dopegyt (Methyldopa) 250mg 50 tablets

Expiration date: 03/2025

The composition and form of issue:

Tablets. 1 tablet contains methyldopa 250 mg

(in the form of methyldopa sesquihydrate 282 mg) 

auxiliary substances: ethyl cellulose magnesium stearate starch corn stearic acid sodium carboximetilkrahmal (type A) talc 

in dark glass bottles of 50 PCs. in cardboard pack 1 bottle.

Method of application and dose:

Inside, before or after a meal.

The dose should be selected for each patient individually.

Initial dose Dopegyt for adults — 250 mg 2-3 times a day for the first 2 days. Thereafter, the daily dose may be increased or reduced, depending on the degree of blood pressure lowering, in steps of 250 mg, with 2-day intervals. To reduce the severity of sedation first increase evening dose. The usual maintenance dose is 500-2000 mg/day in 2-4 reception. The maximum daily dose is 2000 mg (2 g). If the dose of 2000 mg/day is not an effective decrease in blood pressure, it is recommended to use in combination with other antihypertensive agents.

After 1-3 months of treatment may develop tolerance. Effective BP control can be restored by adding a diuretic or increasing the dose Dopegyt.

Elderly patients: the initial dose should be as low as possible, no more than 2 table. 250 mg/day, because these patients often occurs sedative effect. If necessary, the dose can be increased every 2 days to a maximum daily dose of 2000 mg should not be exceeded.

Patients with impaired renal function should use lower doses. In mild renal failure (glomerular filtration rate (GFR) >50 ml/min) should be kept the interval between doses 8 hours under moderate insufficiency (GFR =10-50 ml/min) the interval should be 8 to 12 hours and with severe renal failure (GFR <10 ml/min) — 12-24 hours

Since methyldopa is removed with hemodialysis, after this procedure, the patient should be given an additional dose of 250 mg to prevent blood pressure increase.

The recommended initial dose of methyldopa in children is 10 mg/kg/day in 2-4 reception. If necessary, the daily dose can be gradually increase (to a maximum of 65 mg/kg) at intervals of not less than two days.

Dopegyt
(Methyldopa)
250mg
50
tablets