Expiration date: 05/2027

Quantity in package: 50

Dosage form:  tablets

Composition

1 tablet contains:

active ingredients: peppermint oil 580 µg, 7.5 mg phenobarbital, ethyl ester of ?-bromsulfaleinovy acid 8.2 mg,

excipients: beta-cyclodextrin, potato starch, lactose monohydrate, microcrystalline cellulose, magnesium stearate.

Pharmacological action

Corvalol has a sedative, antispasmodic, vasodilator effect.

Pharmacodynamics

Phenobarbital has a sedative and mild hypnotic effect. It helps to reduce the excitation of the Central nervous system and facilitates the onset of natural sleep. Ethylbromoacetate, has a sedative and antispasmodic action. Peppermint oil has a reflex vasodilating and antispasmodic activity.

Indications

As a sedative and vasodilator:

• functional disorders of the cardiovascular system;
  
• neurosis-like conditions accompanied by increased irritability;
  
• sleep disorders;
  
• tachycardia;
  
• the state of excitation with prominent autonomic manifestations.
  

As an antispasmodic: spasms of the intestine.

Use during pregnancy and breast-feeding

Appointment of the drug Corvalol during pregnancy is possible only on strict indications. If necessary, the appointment of the drug during breastfeeding should decide on the termination of breastfeeding.

Contraindications

Hypersensitivity to the components of the drug Corvalol; expressed violations of kidney and/or liver.

Side effect

The pills are usually well tolerated. In some cases, during the day there may be drowsiness and light dizziness.

With long-term use of high doses may develop chronic bromine poisoning, manifestations of which are: depression, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, impaired coordination.

Interaction

Drugs that inhibit the Central nervous system, enhance the effect of the drug.

Phenobarbital (inducer of microsomal oxidation) can reduce the effectiveness of drugs metabolized in the liver (including coumarin derivatives, griseofulvin, glucocorticosteroids, oral contraceptives); enhances the action of local anesthetic, analgesic and hypnotic agents. The drug increases the toxicity of methotrexate.

The effect of the drug is enhanced by the use of drugs valproic acid.

How to take, course and dosage

The dose is set individually. Take inside, before meals, drink water. Adults are usually prescribed 1-2 tablets 2 times a day. In tachycardia, a single dose can be increased to 3 tablets. The maximum daily dose is 6 tablets.

The duration of the drug is set by the doctor individually.

Overdose

Symptoms: CNS depression, nystagmus, ataxia, lowering blood pressure, excitation, dizziness, weakness, chronic bromine intoxication (depression, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, impaired coordination of movements).

Treatment: discontinuation of the drug, gastric lavage and symptomatic therapy, CNS oppression-caffeine, nicetamide.

Special instruction

Experience with the drug in children under 18 years old is absent.

During the use of the drug should not drink alcohol.

It is recommended to refrain from engaging in potentially dangerous activities that require increased concentration and speed of psychomotor reactions (including driving and working with complex mechanisms).