Expiration date: 04/2026
Dosage form
the crystalline powder is white or almost white.
Composition
Active substance: Sulfanilamide (streptocide) – 5.0 g.
Pharmacological action
Sulfanilamide is an antimicrobial bacteriostatic agent. The mechanism of action is associated with competitive antagonism with paraaminobenzoic acid (pabc) and inhibition of dihydroperoatsintetase, which leads to a violation of the synthesis of dihydrofolic acid, and then tetrahydrofolic acid, resulting in impaired synthesis of nucleic acids of microorganisms. Active against gram-positive and gram-positive microorganisms: Escherichia coli, Shigella spp., Vibrio cholerae, Clostridium spp., Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces spp., Toxoplasma gondii.
Special conditions
During therapy, it is recommended to drink plenty of alkaline. If necessary, at the same time prescribe antimicrobials inside. With the appearance of hypersensitivity reactions, treatment should be discontinued. With long-term treatment, it is recommended to systematically monitor the blood picture, kidney and liver function. Read the instructions carefully before using the drug. Save the instruction, you may need it again. If You have any questions, consult your doctor. The medicine you are being treated with is intended for You personally and should not be passed on to others because it can harm them even if they have the same symptoms as You. The effect of the drug on the ability to drive vehicles, mechanisms. Studies of the effect of the drug on the reaction rate in driving or working with other mechanisms have not been conducted. Taking into account the side effects of the drug (dizziness), care should be taken when managing TRANS - port agents, mechanisms.
Indications
As part of the complex therapy: purulent wounds, infected burns (I-II degree) and other purulent-inflammatory processes of soft tissues.
Contraindications
Hypersensitivity to sulfanilamidam, diseases of the blood, oppression kostnomozgovy blood, anemia, congestive heart failure, hyperthyroidism, renal/hepatic failure, azotemia, porphyria, congenital deficit glukozo-6-fosfatdegidrogenaza, pregnancy, breastfeeding.
With caution: children under 3 years.
Use during pregnancy and breastfeeding
Contraindicated in pregnancy and breastfeeding.
Drug interaction
Myelotoxic drugs increase the manifestation gematotoksichnosti drug.
Dosage
Externally, in the form of powder for external use is applied directly to the affected surface, bandages are carried out in 1-2 days. Maximum doses for adults: single dose – 5 g, daily dose – 15 g. For children older than 3 years: single dose – 300 mg, daily dose – 300 mg. With deep wounds are made in the wound cavity 5-10-15 g powder for external use. If after treatment there is no improvement or new symptoms appear, you should consult your doctor.
Overdose
Symptoms: nausea, vomiting, intestinal colic, dizziness, headache, drowsiness, depression, fainting, confusion, visual impairment, fever, hematuria, crystalluria, with prolonged overdose – thrombocytopenia, leukopenia, megaloblastic anemia, jaundice. Treatment: drinking plenty of fluids, in case of accidental ingestion – gastric lavage
