Expiration date: 03/2026

The composition and form of issue:

1 rectal suppository contains tribenoside 400 mg and lidocaine 40 mg, in blistere 5 PCs., in box 2 blisters.

100 g of the cream — tribenoside 5 g of lidocaine 2 g in tubes of 30 grams in a box 1 tuba.

Pharmacological action:

Has anti-inflammatory, mestnoanesteziruyuschee, protivozudnoe activity. Reduces the permeability of capillaries, improves microcirculation, increases tone of veins of the rectum.

Pharmacokinetics:

After rectal application Cmax (1 µg/l) tribenozida achieved after 2 h of lidocaine (0, 7 µg/l) — 112 min. Bioavailability of tribenoside is 30% of the observed ingestion of lidocaine — 50%. If you use cream systemic absorption was 2-20% of tribenoside. Tribenozid and lidocaine rapidly metabolised in the liver, are excreted mainly in the urine.

Description pharmacological action:

Reduces symptoms of hemorrhoids (pain, pain, itching).

Indications:

External and internal hemorrhoids.

Contraindications:

Hypersensitivity.

Application of pregnancy and breast-feeding:

With caution during pregnancy, especially in the first trimester. In the period of breast-feeding may use without cessation of breastfeeding if the expected effect therapy outweighs the potential risk to the child.

Side effects:

In individual cases, a slight burning sensation, pain, increased peristalsis of the bowel.

Method of application and dose:

Rectal. Until the disappearance of acute symptoms — 1 supp. or 1 dose of the cream 2 times a day (morning and evening), then the dose can be reduced and the drug administered 1 time per day. 30 g of cream is enough for about 20-30 applications.

Precautions:

During the period of treatment should pay special attention to the hygiene of the anal region to avoid excessive strain during bowel movements and taking measures to maintain soft stools.