Expiration date: 10/2026

The composition and form of issue:

1 vial with dry substance for injection contains interferon Alfa-2b 0,5 1 3 or 5 million IU, 5 mg of donor albumin, and 9.5 mg of sodium chloride in packs of 10 pieces with ampulnam knife or scarifier or in a contour acheikova package 5 or 10 PCs.

Indications:

Viral hepatitis B, C, D, viral, viral-bacterial and Mycoplasma meningoencephalitis, viral conjunctivitis, keratoconjunctivitis, keratitis, keratouveitis, kidney cancer stage IV, hairy cell leukemia, malignant lymphomas, Kaposi's sarcoma, skin cancer (basal cell and squamous cell), keratoacanthoma, multiple sclerosis, lymphoblastic leukemia in children, respiratory papillomatosis of the larynx.

Contraindications:

Hypersensitivity.

Application of pregnancy and breast-feeding:

Contraindicated.

Side effects:

Fever, chills, leukopenia and thrombocytopenia, skin allergic reactions.

Method of application and dose:

V/m (in the hearth or under the lesion), subconjunctival, locally. Acute hepatitis B and 1 million IU/m 2 times a day for 5-6 days (course — 15 million IU) chronic active hepatitis B and 1 million IU/m 2 times a week for 1-2 months chronic active hepatitis B and D (with signs of cirrhosis of the liver) — 250-500 thousand IU / day in/m 2 times a week for 1 month hairy cell leukemia — 3-6 million IU daily for 2 months, (course — 420-600 million IU) kidney cancer — 3 million IU daily for 10 days (course 120-300 million IU) stromal keratitis and keratomalacia — subconjunctival 60 thousand IU in a volume of 0.5 ml daily (course of 15-25 injections).

Special instructions:

Contains not more than 5 mg of albumin from the blood donor, the last control in the absence of HBs-antigen and antibodies to HIV.