• Postinor (Levonorgestrel) 0.75mg 2 tablets

Expiration date: 09/2023

Structure and Composition:

One tablet contains 0.75 mg levonorgestrel

Excipients: silica colloidal anhydrous magnesium stearate, talc, corn starch, potato starch, lactose monohydrate

in blisters 2 pcs. 1 pack per box.

Description pharmaceutical form:

Flat tablets almost white, disk-shaped with beveled edges with cut, labeled «INOR» ​​on one side.

Characteristic:

The synthetic progestogen with a contraceptive effect.

Pharmachologic effect:

It has a pronounced progestagenic and antiestrogenic properties. It causes inhibition of ovulation and changes in the endometrium, prevents implantation of a fertilized egg. It increases the viscosity of the cervical mucus, which hinders the promotion of sperm.

Pharmacokinetics:

When ingestion rapidly and completely absorbed from the gastrointestinal tract. Cmax in plasma observed after 1.6 hours and is 14.1 ng / ml. Associated with albumin and globulin, sex hormone binding. Penetrates into breast milk: breastfeeding about 0.1% of levonorgestrel with breast milk ingested by the newborn. Levonorgestrel is metabolized in the liver, its biotransformation corresponds metabolize steroids. Levonorgestrel pharmacologically active metabolites are unknown. Blood concentration is reduced in phase 2, T1 / 2 2-7 h of 60% of the drug in the form of metabolites excreted in the urine and 40% -. faeces.

Clinical Pharmacology:

Contraceptive Efficacy decreases as the time elapsed between sexual intercourse and reception preparation: it is 95% at the reception in the first 24 hours, 85% - between 24 and 48 hours, and 58% - between 48 and 72 hours.

Under the recommended doses of levonorgestrel has no significant effect on blood clotting factors, fat and carbohydrate metabolism.

Testimony:

Emergency postcoital contraception in the following emergency situations:

1. If there was unprotected sexual intercourse

2. If the application of a method of contraception can not be considered reliable, for example:

  • Gap, slippage, or incorrect use of a condom
  • Shear rupture or premature removal of a diaphragm or cervical plate (pessary)
  • An unfortunate use of the method of the interrupted sexual intercourse
  • Incorrect calculation of ovulation days in the case of the calendar method
  • The loss or removal of intrauterine contraceptive
  • Skip 3 or more pills at constant reception of hormonal contraceptive

3. Rape.

Contraindications:

Hypersensitivity to the drug, severe liver disease or biliary tract, genital bleeding of unknown etiology (including metrorrhagia), arterial and venous thrombosis, thromboembolism (history), pregnancy (including supposed) relative contraindication - period puberty.

Children. Appointment of children postinor tablets is not recommended as currently there is little data on the use of the drug by children under 16 years of age.

Application of pregnancy and breastfeeding:

Contraindicated during pregnancy.

Lactation. Possible effects on infants can be minimized if a nursing mother takes two tablets immediately after breastfeeding, and after taking the drug is not breastfeeding.

Side effect:

From endocrine system: dysmenorrhea (including bleeding intermenstrual discharge), the feeling of tension of the mammary glands, delayed menstruation (the majority of women next menstruation occurs at the usual time, but if the missed period is more than 5 days, exclude pregnancy).

From the digestive system: nausea, vomiting, diarrhea.

Other: fatigue, dizziness.

Drug Interactions:

While the use of liver enzyme inducers metabolism of levonorgestrel is enhanced. In a joint application with ampicillin, rifampin, tetracycline, barbiturates, primidone, phenytoin, carbamazepine, ritonavir, rifabutin, griseofulvin Postinor contraceptive effect may be reduced. At simultaneous application with cyclosporine increases the toxicity of the latter due to the inhibition of its metabolism.

Dosage abd administration:

The inside is not liquid, squeezed small amounts of water, regardless of the meal, after intercourse within 48 hours, but not later than 72 hours, take 1 tablet. drug and 12 hours after the first dose has to take one tablet.

It is not recommended to apply the method of emergency contraception more than 1 time in 4-6 months.

If within 2 hours after administration of the tablet vomiting occurred, a pill should be repeated.

Postinor Tablets can be used on any day of the menstrual cycle.

Overdose:

about serious adverse effects of data after receiving a large dose of the contraceptive is not. Symptoms: nausea, menstrual disorders.

Treatment: symptomatic. No specific antidote.

Special instructions:

Apply strictly prescribed by a doctor to avoid complications.

Postinor recommended for women with a regular menstrual cycle. postinor re-use of the drug should be avoided during the same menstrual cycle, because of possible violations of the menstrual cycle. Do not use as a means of regular and continuous contraception, as This leads to lower efficacy and frequent adverse reactions.

Postinor tablets do not replace regular contraception. With regular sex life is recommended to use other methods of contraception.

In case of uterine bleeding gynecological examination is recommended.

If pregnancy on background Postinor yet developed, or postinor was adopted against the background of an existing pregnancy, the risk of adverse effects on the fetus has not been established.

The drug has no negative impact on the ability to drive a car and perform work that requires a high rate of mental and physical reactions.

Postinor
(Levonorgestrel)
0.75mg
2
tablets

  • $20.00