Expiration date: 06/2025
Water for injections ampoules / Aqua pro injectionibus
Dosage form
Water
Composition
In 1 ml of solvent for the preparation of pharmaceutical forms for injections contains: Water for injections 100%.
Packaging
In the ampoule of 2 or 5 ml solvent. In the package of 10 or 100 vials.
Pharmacological action
Water for injections is the universal solvent, the basis not only for various transfusion preparations, but also in biological fluids and tissues (blood, lymph, plasma cells, etc.), necessary for regular metabolic processes.
In normal conditions water is excreted with urine, feces, sweat and breath. Loss of fluid through sweat, breathing and feces takes place independently of the introduction of the liquid. Maintenance of adequate hydration requires 30-45 ml/kg/ water in adults and in children, 45-100 ml/kg in infants - 100-165 ml/kg.
Water for injections is used to prepare infusion and injection solutions, providing optimum conditions for compatibility and efficiency of substrates and water.
Water for injections is hypotonic medium in relation to the tissues of the body, so in its pure form causes somewhat greater irritation than isotonic solutions or prepared on the basis of water for injection solution (for parenteral administration, eye drops, etc.). When administered into a vein of pure water for injection can occur hemolysis, however, the slow introduction of small quantities of practically does not render such action. So the water is safe for injection as a solvent of drugs (in accordance with the instructions for use), prepared with water for injection.
Testimony
The solvent for preparing the preparation of sterile infusion (injection) solutions from powders, freeze-dried and concentrates for p/to the in/m, in/in the introduction.
- For washing wounds and moistening of dressing materials.
Contraindications
Contraindicated in case to prepare the drug solution specify a different solvent.
Method of application and doses
Intravenously, drip in the form of "shock" therapy or injection, according to instructions for use of added infusion solutions and concentrates, concentrates for preparation of infusions, injection solutions, powders, and dry substances for preparation of injections.
Daily dose and infusion rate should meet the dosage instructions for the added medicinal products.
Externally for washing wounds and moistening of dressing materials.
Preparation of solutions of drugs with water for injection must be done under sterile conditions (opening of ampoules, filling the syringe and containers of medicines).
Special instructions
Do not mix with water oil solutions for injections, external funds to ablate.
Means, the concentration of which should remain within certain limits, is diluted with water for injections only within the specified limits.
Water for injection can not be directly injected or introduced in the form of infusion due to the lack of substances with low osmotic pressure (the risk of hemolysis!).
Interaction
Incompatibility of medicinal products with water is practically nonexistent, as if the substance incompatible with water, it will be incompatible with the aqueous environment of the body.
When mixed with other medicinal products (infusion solutions, concentrates for preparation of infusions, injection solutions, powders, dry substances for preparation of injections), visual checking is necessary for compatibility (can take place himicheskaja or therapeutic incompatibility).
Storage conditions
Store at temperatures from 5°C to 25°C. Freezing is not allowed.
Shelf life
4 years.
