Expiration date: 05/2025

The composition and form of issue:

1 tablet contains papaverine hydrochloride 0.04 g in a contour cell-free package of 10 PCs.

1 ampoule with 2 ml of solution for injection-40 mg in a package of 10 PCs.

Pharmacological action:

It blocks phosphodiesterase, causes camp accumulation and decrease of calcium content in the cell, relaxes smooth muscles.

Indications:

Spasms of cerebral vessels, angina, endarteritis, cholecystitis, pylorospasm, spastic colitis, renal colic.

Contraindications:

AV blockade.

Side effect:

AV blockade, ventricular extrasystole, hypotension, constipation, drowsiness.

Dosage and administration:

Inside-0, 04-0, 06 g 3-5 times a day. The highest single dose-0, 4 g, daily-0, 6 g.

P/K-1-2 ml 2-4 times a day in/in, slowly-1 ml, pre-dilute 2% solution in 10-20 ml isotonic sodium chloride solution.