Expiration date: 07/2023
Composition per 100 g of gel:
Active ingredient: azelaic acid -20.0 g,
Excipients: carbomer 980-1.0 g, benzoic acid-0.1 g, disodium edetate dihydrate-0.1 g, ceramides LS-0.1 g, isopropyl-mirisgate-1.0 g, polysorbate-20 -1.5 g, propylene glycol-12.0 g, sodium hydroxide-0.2 g, water-up to 100.0 g
It causes a moderate cytostatic effect (by inhibiting the synthesis of cellular proteins), which is manifested in the normalization of keratinization processes in the wall of the follicles of the sebaceous glands, has an antimicrobial effect (primarily against Propionibacterium acnes and Staphylococcus epidermidis) both on the surface of the skin and in the sebaceous glands, as well as anti-inflammatory effect (reducing the metabolism of neutrophil granulocytes and their production of free radical oxygen forms-important factors in maintaining the inflammatory process).
With prolonged use of the drug, no resistance of microorganisms is formed. Azelaic acid dose-dependently inhibits the growth and viability of abnormal melanocytes. The therapeutic effect in hyperpigmentation (melasma) is due to the inhibition of DNA synthesis and/or suppression of cellular respiration of abnormal melanocytes.
- Common acne (acne vulgaris),