Expiration date: 08/2024

Active substance: Ethyl N-phenylacetyl-L-prolylglycine

The drug forms: white tablets, round shape with beveled

Pharmachologic effect:  nootropic

Pharmacodynamics

Noopept® has nootropic and neuroprotective properties. It improves learning ability and memory, working on all phases of processing: the initial processing of information, consolidation, extraction. Prevents the development of amnesia induced by electric shock, blockade of central cholinergic structures glutamatergic receptor systems, deprivation of paradoxical sleep phase.

Neuroprotective (protective) effects of the drug Noopept® is to increase the stability of brain tissue to damaging influences (trauma, hypoxia, electroconvulsive, toxic) and the weakening of the degree of damage to brain neurons. The drug chamber to reduce the volume of thrombotic stroke models and prevents neuronal death in the tissue culture of cerebral cortex and cerebellum, subjected to the action of neurotoxic glutamate concentrations, free-radical oxygen.

Noopept® has an antioxidant effect, blocking of voltage dependent calcium channels of neurons, weakening the neurotoxic effects of excessive calcium, improves the rheological properties of blood, having antiagregatsionnym, fibrinolytic, anticoagulant properties.

Nootropic drug effect is associated with the formation tsikloprolilglitsina similar in structure to endogenous cyclic dipeptide possessing antiamnestic activity and the presence holinopozitivnogo action.

Noopept® transcallosal increases the amplitude of the response, facilitating associative links between the hemispheres of the brain at the level of cortical structures. It helps restore memory and other cognitive functions, disturbed as a result of the damaging effects - brain trauma, local and global ischemia, prenatal damage (alcohol, hypoxia).

The therapeutic effect of the drug in patients with organic CNS disorders manifested starting with 5-7 days of treatment. First implemented in the existing spectrum of activity of the drug Noopept® anxiolytic and stimulating light effects, manifested in the reduction or disappearance of anxiety, irritability, affective lability, sleep disorders. After 14-20 days of therapy revealed a positive effect of the drug on cognitive function, attention and memory options.

Noopept® has vegetonormalizuyuschim action, helps to reduce headaches, orthostatic disorders, tachycardia.

When you remove the drug is observed withdrawal. It does not have a damaging effect on the internal organs; It does not lead to a change in the cellular composition of the blood and biochemical parameters of blood and urine; has no immunotoxic, teratogenic, does not exhibit mutagenic properties.

Pharmacokinetics

Ethyl N-phenylacetyl-L-prolylglycine, absorbing in the digestive tract, in an unmodified form enters the systemic circulation, penetrates through the BBB, the brain is determined in larger concentrations than in the blood. Tmax averages 15 minutes. T1 / 2 of plasma -. 0.38 h partly preserved in unchanged form, partially metabolized with the formation of phenylacetic acid, and fenilatsetilprolina tsikloprolilglitsina. It has a high relative bioavailability (99.7%), not accumulates in the body, it does not cause drug dependence.

Indications Noopept® drug

Violations of memory, attention and other cognitive functions, and emotionally labile disorder, including in elderly patients, under the following conditions and diseases:

  • consequences of traumatic brain injury;
  • post-concussion syndrome;
  • cerebral vascular insufficiency (encephalopathy different genesis);
  • asthenic disorders;
  • other conditions with symptoms of decline of intellectual efficiency.

Contraindications

  • hypersensitivity to the drug;
  • lactase deficiency, lactose intolerance, glucose-galactose malabsorption;
  • expressed human liver and kidneys;
  • pregnancy;
  • lactation;
  • age 18 years.

Side effects

Allergic reactions are possible. In patients with hypertension, mostly severe, rise in blood pressure may occur in patients receiving the drug.

Interaction

Not applicable Noopept® drug interaction with alcohol, drugs and antihypertensive drugs and drugs stimulating effect.

Dosing and Administration

Inside, after a meal.

Treatment started with a dose of 20 mg, 10 mg distributed into 2 doses (morning and afternoon). In case of insufficient efficacy and good tolerability of the drug dose was increased to 30 mg (cm. "Special instructions") and distributed into 10 mg to 3 divided doses throughout the day. Do not take the medication within 18 hours.

The duration of a course of treatment - 1.5-3 months. If necessary, a second course may be carried out after 1 month.

Overdose: Specific manifestations have not been established.

Special instructions

If necessary, increase the dose (30 mg / day), long-term use, as well as the simultaneous use of other drugs, the emergence of adverse events or deterioration should consult a doctor.

Effects on ability to drive and use machines. Noopept® does not affect the ability to drive machinery and vehicles.

Release Form: Tablets, 10 mg. In blisters made of PVC film and aluminum foil printed lacquered, 25 pcs. 2 blisters in a pack made of cardboard.

Manufacturer: "Lekko" CJSC. 601125, Vladimir region., Petushki district, pos. Volginsky.

Conditions of supply of pharmacies: without recipe.

Storage conditions

In a dry, dark place at a temperature no higher than 25 ° C.

Keep out of the reach of children.

The shelf life: 3 years.

Do not use beyond the expiration date printed on the package.

Noopept
10mg
50
tablets

  • $15.00