Expiration date: 03/2024

Active substance: Choline alfostserat. 

Structure and Composition:

The capsules. One capsule contains glycerylphosphorylcholine hydrate 400 mg

Excipients: glycerol, purified water

Capsule shell: gelatin glycerol Medical methyl parahydroxybenzoate Propyl red iron oxide titanium dioxide Purified water

in blisters of  14 pieces. In the paper cartons 1 package or in the banks of dark glass of 14 pieces. In the paper cartons 1 bank.

Solution for intravenous and intramuscular administration. 1 ml contains glycerylphosphorylcholine hydrate 250 mg

Excipients: Water for Injection

in vials of 4 ml cardboard pack 3 or 5 vials or contour bezgyachakova or packaging in blisters to 3 or 5 ampoules per stack of cardboard packaging 1 or 2.

Description pharmaceutical form:

The solution for intravenous and intramuscular injection: clear, colorless liquid.

Capsules: soft, gelatinous, oblong, from red to brown.

The contents of capsules - oily, clear, colorless or slightly colored liquid.


Absorption - 88%, easily penetrate the BBB (if administered orally in the brain concentration of 45% of that in plasma). Light appears mainly in the form of carbon dioxide (85%), and through the intestine and kidney (15%).

Description of the pharmacological actions:

Central holinostimulyator, in which the composition contains 40.5% metabolically protected choline (metabolic protection helps liberatiou choline in the brain). When ingested, it is cleaved by the action of enzymes in the glycerophosphate choline and choline is involved in the biosynthesis of acetylcholine - one of the major mediators of nervous excitement glycerophosphate is a precursor of phospholipids (phosphatidylcholine) neuronal membrane. It provides phosphatidylcholine and acetylcholine synthesis in neuronal membranes, improves blood flow and increases the metabolic processes in the CNS, to activate the reticular formation. Increases blood flow linear velocity on the side of a traumatic brain injury, promotes the normalization of the space-time characteristics of spontaneous brain bioelectrical activity has a positive effect on the cognitive and behavioral responses in patients with cerebrovascular diseases.

It improves brain function, affecting the pathogenetic factors of involutional psychoorganic syndrome alters the composition of the phospholipid membranes of neurons and increases cholinergic activity. Dose-dependently stimulates the release of acetylcholine by participating in the synthesis of phosphatidylcholine (membrane phospholipid), improves synaptic transmission, plasticity of the neuronal membrane receptor function. No effect on the reproductive cycle and has no teratogenic, mutagenic effect.


  • acute and recovery periods of severe traumatic brain injury and ischemic stroke, hemorrhagic stroke recovery period occurring with a focal hemispheric symptoms or symptoms of brain stem
  • psycho-organic syndrome on the background of involution and degenerative changes in the brain
  • chronic cerebrovascular insufficiency
  • cognitive disorders (disorders of mental function, memory, confusion, disorientation, decrease in motivation, initiative and ability to concentrate), including: dementia and encephalopathy
  • psevdomelanholiya senile.


  • hypersensitivity
  • pregnancy
  • breast-feeding.

Application of pregnancy and breastfeeding:

Contraindicated during pregnancy. At the time of treatment should stop breastfeeding.

Side effect:

Allergic reactions, nausea (due to dopaminergic activation).

Drug Interactions:

Not found.

Dosage and administration:

V / m in / or inside.

In acute conditions: in / m or / in (slow) and 1 g (. 1 amp) per day for 10-15 days, then move on to the capsules inside of 0.8 g (2 caps.) In the morning and 0 4 g (1 capsule). day for 6 months.

In chronic conditions: the interior of 0.4 g (1 capsule). 3 times a day, preferably before meals. The duration of treatment is 3-6 months.


Symptoms: diarrhea phenomenon.

Treatment: gastric lavage, activated charcoal, symptomatic therapy.

Special instructions:

If nausea occurs, the dose should be reduced after ingestion.

Cerepro has no effect on the speed of psychomotor reactions.