Expiration date: 01/2026
Release form
Film-coated tablets, 500 mg - 20 pcs with instructions for medical use in the package
Dosage form
oblong biconvex tablets, coated with a yellow film shell, with a risk on one side. On the cross section: from light yellow to yellow or yellow with a greenish tinge of color.
Composition
1 tablet contains:
active substance:
N-methyl-4-benzylcarbamidopyridinium iodide (Enisamy iodide) - 500.0 mg;
excipients (core): lactose monohydrate, microcrystalline cellulose 101, sucrose (sugar), povidone K-17, co-povidone, crospovidone, talc, calcium stearate. excipients (film shell): Aquarius Prime BAN314047 Yellow: hypromellose, titanium dioxide, caprylate/caprylate (caprylic/caprine triglyceride), iron oxide yellow dye, iron oxide red dye, quinoline yellow dye.y is yellow.
Pharmacotherapeutic group
antiviral agent
Pharmacodynamics
Enisamy iodide is an antiviral agent derived from isonicotinic acid. Effectively suppresses the action of influenza viruses and other pathogens of acute respiratory viral infections (ARVI) due to the direct (inhibitory) effect on the process of virus penetration through the cell membrane.
It has interferogenic properties, helps to increase the concentration of endogenous interferon (interferon alpha and interferon gamma) in blood plasma by 3-4 times. Increases the body's resistance to viral infections.
Reduces acute clinical manifestations of viral intoxication, helps to reduce the duration of the disease.
Pharmacokinetics
After oral administration of enisamy iodide quickly enters the bloodstream, its maximum concentration in the blood is observed 2-2.5 hours after consumption. Enisamy iodide and its metabolites circulate in the bloodstream for a long time (half-life is 13.5-14 hours), are metabolized in the liver and are rapidly excreted from tissues (half-life is 2-3 hours). It is excreted by 90-95% in the urine in the form of metabolites.
Indications
Treatment of influenza and other acute respiratory infections, including as part of complex therapy.
Contraindications
Hypersensitivity to any of the components of the drug. Lactase deficiency, lactose intolerance, glucose-galactose malabsorption. Sucrose/isomaltase deficiency, fructose intolerance. Children under 12 years of age, pregnancy, breastfeeding period. The presence of allergic reactions regardless of the nature of the allergen in the anamnesis. Severe organic damage to the liver and kidneys.
Use during pregnancy and breastfeeding
It is contraindicated during pregnancy and breastfeeding.
Method of administration and dosage
Start treatment when the first signs of the disease appear. If there is no improvement after 3 days of treatment, or the symptoms worsen, or new symptoms appear, it is necessary to consult a doctor. Use the drug only according to the indications, the method of application and in the doses specified in the instructions.
The drug NOBAZIT FORTE is taken orally after eating, without chewing.
Adults 500 mg (1 tablet) 3 times a day. The maximum single dose is 1 g (2 tablets), the daily dose is 2 g (4 tablets).
The recommended course of treatment is from 5 to 7 days.
For children from 12 years of age, 250 mg (1/2 tablet) 3 times a day for 7 days.
Side effects
Allergic reactions: hypersensitivity reactions, including skin rashes, urticaria, angioedema, itching.
From the gastrointestinal tract: dryness and bitter taste in the mouth, swelling of the oral mucosa, hypersalivation, yellow staining of the tongue, nausea, vomiting, heartburn, abdominal pain, heaviness in the right hypochondrium, diarrhea, bloating.
From the respiratory system: shortness of breath, irritation of the throat.
In the post-registration period, the following adverse reactions were noted in isolated cases: headache, dizziness, weakness, fluctuation of blood pressure.
If you experience side effects listed in the instructions, or they worsen, or you notice any other side effects not listed in the instructions, inform your doctor.
Overdose
In case of an overdose of the drug, it is possible to increase the side effects described in the relevant section. When they appear, gastric lavage and symptomatic treatment are performed.
Drug interaction
The interaction with other drugs has not been sufficiently studied.
The drug NOBAZIT FORTE enhances the effect of antibacterial and immunomodulatory agents. It is advisable to combine this drug with ascorbic acid and other vitamins. Also, the drug NOBAZIT® FORTE can be prescribed temporarily using recombinant interferon.
If you are using the above or other medications (including over-the-counter ones), consult your doctor before using the preparation NOBAZIT® FORTE.
Special conditions
The drug should be prescribed with caution to patients with thyroid diseases, especially with hyperthyroidism.
Influence on the ability to drive vehicles, mechanisms
Taking enisamium iodide does not affect the ability to drive vehicles and mechanisms.
Storage temperature
from 2℃ to 25℃
