Expiration date: 07/2025

Active substance: Flupentixol

Structure and Composition:

1 tablet contains flupenthixol dihydrochloride 0.5, 1 or 5 mg of a plastic bottle 50 or 100 pieces. respectively.

Pharmachologic effect:

Blocks dopamine receptors in the brain.

Testimony:

Average dose (3 mg or more): psychotic states with a predominance of hallucinations, paranoid delusions, disturbances of thought, accompanied by apathy, anergy, autism.

Small doses (3 mg): depression, mild to moderate severity, accompanied by anxiety, fatigue, lack of initiative chronic neurotic disorders with anxiety, depression, apathy psychosomatic disorders with asthenic manifestations of acute and situationally caused anxiety and state of emotional stress (without the need for sedation , for suspected abuse of tranquilizers).

Contraindications:

Acute poisoning with alcohol, barbiturates, opiates, coma, agitation, hyperactivity.

Application of pregnancy and breastfeeding:

Contraindicated. Nursing mothers should stop breast-feeding.

Side effect:

There are extrapyramidal disorder, tardive dyskinesia, insomnia or drowsiness, neuroleptic malignant syndrome, changes in liver function tests.

Drug Interactions:

Increases (in high doses) effects of alcohol, barbiturates and other CNS depressants reduces -. Levodopa and other adrenergic substances.. It weakens the hypotensive effect of guanethidine and its analogues. The risk of extrapyramidal disorders increase metoclopramide and piperazine.

Dosage and administration:

Inside. For the treatment of psychoses: doses (3 mg or more) are selected individually depending on the patient usually start with small doses, and then rapidly increase the dosage until the optimum effect recommended initial daily dose - 5-15 mg in 2-3 doses, if required increase the dose to 40 mg / day for maintenance therapy - 5-20 mg / day (can be in the morning, once).

For the treatment of borderline conditions: doses up to 3 mg - 1 first time in the morning 1 mg or 0.5 mg 2 times daily after 1 week dose can be increased (if necessary) to 2 mg / day daily dose of 2 mg (3 mg) was divided into several times when the effect of the maximum dose (3 mg per day) is absent for 1 week, the drug overturned.

Precautionary measures:

With caution is prescribed for seizures, chronic hepatitis, cardiovascular disease parties, driving a car or other. Mechanisms (especially at the beginning of treatment). In the pre-treatment with neuroleptics or tranquillizers (a sedative) should stop taking them gradually. During prolonged treatment, especially with high doses, careful monitoring of patients.