Expiration date: 03/2025

The composition and form of issue: 

Tablets. 1 tablet contains:

allopurinol 100 mg

excipients: lactose monohydrate potato starch povidone K 25 talc magnesium stearate sodium carboximetilkrahmal type A 

banks in a dark glass for 50 PC. in the paper cartons 1 Bank.

Tablets. 1 tablet contains:

allopurinol 300 mg

excipients: magnesium stearate silicon dioxide colloidal anhydrous gelatin sodium carboximetilkrahmal type And ICC 

in dark glass bottles to 30 PCs. in cardboard pack 1 bottle.

Method of application and dose:

Inside, after eating, drinking plenty of water.

Daily urine volume should be greater than 2 l, and the urine reaction — neutral or slightly alkaline. Daily dose of over 300 mg should be divided into several intakes.

Adults. To reduce the risk of possible side effects it is recommended to start the course with an intake of 100 mg 1 time per day. If necessary, the daily dose can be gradually increased (in the control of uric acid level in the blood serum at intervals of 1-3 weeks) in steps of 100 mg to achieve the desired effect.

The usual maintenance dose is 200-600 mg per day. In some cases it may be necessary to increase the daily dose to 800 mg.

In terms of body mass can be given at 2-10 mg/kg/day.

Cancer patients receiving allopurinol should be started 1-2 days before the start of anticancer therapy. The drug should be given daily at a dose of 600-800 mg for 2-3 days, then continue taking a maintenance dose assigned on the basis of the level of uric acid in the blood serum.

Children. In secondary hyperuricemia associated with malignant diseases of blood system and other organs, as well as some disorders of enzyme functions and the usual daily dose is 10-20 mg/kg depending on the size of the tumor, the number of peripheral blast cells, or the degree of infiltration of the bone marrow.

Elderly patients, and also at infringement of function of kidneys and liver. Older patients should always assign the smallest possible clinically effective dose should always consider the possibility of reduced renal function and/or liver.

Depending on the degree of violation of functions of kidneys and liver dose should be reduced, because in these conditions increases the risk of toxic effects of the drug.

In renal failure dose should be reduced it should not exceed 100 mg/day with Cl creatinine below 20 ml/min Can also be given another dose of 100 mg of the drug every day, and with a longer interval. It is strongly recommended to monitor the level of allopurinol in the blood plasma. This level should not exceed 100 µmol/l (15, 2 mg/l). Allopurinol and its metabolites are excreted in hemodialysis. In the case of hemodialysis 2-3 times a week is recommended a single-dose of 300-400 mg immediately after dialysis, as in the days when hemodialysis is not carried out, the drug should not be entered.



  • Brand: EGIS

  • Availability:
    out of stock