Expiration date: 02/2025

Release form

pills

Composition

1 tablet contains chloroquine 250 mg

Packaging

30 PCs.

Pharmacological action

Antiprotozoal remedy, also has immunosuppressive and anti-inflammatory effect.Delagil cause the death of asexual erythrocytic forms of all species of Plasmodium. Having gametocide action, with the exception of Plasmodium falciparum (shows anthomyiidae action).

Testimony

Malaria (prevention and treatment of all types), extraintestinal amoebiasis, amoebic liver abscess, systemic lupus erythematosus (SLE) (subacute and chronic forms), rheumatoid arthritis, scleroderma, photodermatosis.

Contraindications

Renal and hepatic failure, severe cardiac arrhythmias, depression of hematopoiesis in the bone marrow, porphyrinuria, neutropenia, hypersensitivity to components of the drug, child age to 6 years.

Method of application and doses

Delagil take orally after meals. 

In the treatment of malaria appoint 2-2.75 g per course of treatment: 1 g/first day, after 11-12 hours 0.5 g, the second and third day 0.5-0.75 g per serving. Maximum dosage for adults -1.5 g per serving. Children 6-10 years appoint 0.25 g in the first day, then 0.125 g in the second and third day of treatment. Children 10-15 years – 0.5 g/ first day, then 0.25 g in the second and third day.

Prevention of malaria infection: 0.5 g two times a week, then 0.5 g once a week. In the case of rheumatoid arthritis Delagil taking 0.5 g/ day for 2 admission for 6-8 days. Then daily at 0.25 g for 12 months.

Side effects

• From nervous system: dizziness, psychomotor agitation, headache, insomnia, psychosis, neuropathy, seizures.
  
• From the side of musculoskeletal system: myopathy.
  
• From sensitive analyzers: a hearing disorder, tinnitus, weakening of vision, corneal opacity, retinopathy, violation of accommodation, reversible keratopathy.
  
• On the part of the digestive system: nausea, vomiting, diarrhea, anorexia, abdominal pain of spastic character, lowering of body weight, hepatotoxicity.
  
• From vascular system: possible development of hypotension, cardiomyopathy.
  
• Cutaneous manifestations: dermatitis, pruritus, rash, photosensitivity, skin pigmentation disorders, hair loss.
  

Drug interactions

The combined use of other antimalarial drugs increases the effect Delagila. Cannot be taken in conjunction with the preparations of gold, cytotoxic agents, penicillamine, levamisole, because it may increase the side effects of the drug. When co-administered with MAO inhibitors is the increased toxic effect. Prolonged use Delagila in conjunction with cardiac glycosides may develop glycoside intoxication. Ethanol enhances the toxic effect Delagil on the liver.

Overdose

Overdose of this drug there is loss of consciousness, vomiting, respiratory depression, convulsions, collapse. In case of overdose it is necessary to wash the stomach, take inside the adsorbents. In severe cases of poisoning may use on plasmapheresis and peritoneal dialysis.

Storage conditions

In a dark, dry place at a temperature of 25 degrees Celsius.