Expiration date: 03/2025
Structure and Composition:
One dragee contains active substance:
192 mg of pancreatin (Equivalent amylase - 4500 FIP U lipase - 6000 FIP U protease - 300FIP ED)
50 mg of hemicellulase
25 mg of bile components
Excipients: sodium chloride
shell structure: tsellatsefat (cellulose acetate phthalate) ethyl vanillin castor oil, sucrose, methyl parahydroxybenzoate (methylparaben) propyl parahydroxybenzoate (propylparaben), gelatin, liquid dextrose (glucose liquid), talc, calcium carbonate acacia gum, glycerol (glycerin) macrogol (polyethylene glycol 6000), titanium dioxide
Pills in strips of 10 pieces. a stack of cardboard 2, 4, 6 or 10 strips.
Description pharmaceutical form:
White, glossy, round pills with low odor of vanilla.
Pharmachologic effect:
Compensates for lack of exocrine pancreatic function due to pancreatin and biliary liver function due to gall component.
It has a proteolytic, amylolytic and lipolytic action. Included in the pancreatin enzymes - amylase, protease and lipase - facilitate the digestion of carbohydrates, fats and proteins, which contributes to a more complete absorption in the small intestine. In this respect, practically no different from other enzyme preparations.
The presence of bile acids provides additional opportunities for correction of biliary insufficiency, which is often associated with chronic pancreatitis.
Bile extract choleretic effect, and facilitates absorption of fat soluble vitamins A, E and K, promotes the release of pancreatic lipase.
Hemicellulase enzyme promotes cleavage of fiber that improves digestive processes, reduces the formation of gas in the intestine.
Indications:
lack of exocrine pancreatic function in chronic pancreatitis combined with biliary insufficiency due to various pathological conditions clinically manifest violation of the digestion of food, flatulence, tendency to constipation, as part of combination therapy for:
- Diffuse liver diseases - alcoholic and toxic liver damage, cirrhosis of the liver
- The large losses of bile acids (in patients after cholecystectomy)
- Violation of the circulation of bile acids observed in biliary dyskinesia, overgrowth, malabsorption
- Violation of neurohumoral regulation processes of bile formation and secretion of chronic diseases of the gastrointestinal tract - chronic gastritis, chronic duodenitis, chronic cholecystitis
- to improve food digestion in patients with normal gastrointestinal function in the event of errors in nutrition, as well as in violation of chewing function, forced prolonged immobilization, sedentary lifestyle
- preparations for X-ray and ultrasound examination of the abdominal cavity.
Contraindications:
- Hypersensitivity to the drug
- acute pancreatitis, exacerbation of chronic pancreatitis
- hepatic failure, hepatic coma or precoma
- hepatitis
- hyperbilirubinemia
- jaundice, cholelithiasis
- empyema of the gall bladder, intestinal obstruction
- tendency to diarrhea
- Children under 3 years of age (for a given dosage form).
Precautions: cystic fibrosis, pregnancy.
Side effect:
Allergic reactions (redness of the skin, sneezing, watery eyes), nausea, diarrhea, abdominal pain (including intestinal colic).
With prolonged use at high doses may develop hyperuricemia, giperurikurii.
In children (when taken in high doses) may develop perianal irritation and irritation of the oral mucosa.
Drug Interactions:
In an application enhances the absorption of Pasco, sulfonamides, antibiotics may decrease the absorption of iron.
The simultaneous use of antacids containing calcium carbonate and / or magnesium hydroxide, can reduce the effectiveness Festalum.
Cimetidine enhances the effect of the drug.
Dosage and administration:
The inside is not liquid, during or immediately after a meal, washed down with a small amount of liquid.
Assign 1-2 pills 3 times a day. Higher doses prescribed by the doctor only.
Prior to X-ray or ultrasound - 2 tablets 2-3 times a day for 2-3 days prior to the study.
The dosage regimen in children determined by the physician.
Duration of treatment may vary from a few days (in case of violation of the digestive process due to errors in the diet) to several months or years (permanent replacement therapy if necessary).
