Expiration date: 08/2025

Pharmachologic effect: Enterosorbent

Enterosgel is porous silicon matrix (molecular sponge) hydrophobic nature which is characterized by the sorption effect only with respect to toxic metabolites with medium weight (M.W. 70 to 1000).

Enterosgel has pronounced sorption and detoxification properties. In the lumen of the gastrointestinal drug binds and removes from the body's endogenous and exogenous toxic substances of different nature, including bacteria and bacterial toxins, antigens, food allergens, drugs, poisons, heavy metals, alcohol.

The drug also absorbs the metabolic products of the body, including an excess of bilirubin, urea, cholesterol, lipid complexes, as well as the metabolites responsible for the development of endogenous toxicosis.

Enterosgel does not reduce the absorption of vitamins and minerals, helps to restore the intestinal microflora disturbed and does not affect the motor function.

Pharmacokinetics:

The drug is not absorbed in the gastrointestinal tract.

Provided in unchanged form within 12 hours.

Testiminy:

In adults and children as a means of detoxification:

• Acute and chronic toxicity of various origins
  
• Acute intoxication potent and poisonous substances (including drugs, ethanol, alkaloids, salts of heavy metals)
  
• In the complex therapy of acute intestinal infections of any origin (including poisoning, salmonella, dysentery, infectious origin diarrheal syndrome, dysbiosis)
  
• In combined therapy for septic diseases accompanied by severe intoxication
  
• Food and drug allergy
  
• Hyperbilirubinemia (viral hepatitis, jaundice of different origin)
  
• Hyperasotemia (chronic renal failure)
  
• Prevention of chronic intoxication in workers of hazardous industries.
  

Dosage and administration:

Enterosgel as an aqueous slurry or paste to be taken orally 1-2 hours prior to a meal (taking other drugs) or after a meal. To prepare the aqueous slurry should the amount of drug necessary to thoroughly grind 1/4 cup of water. it is recommended to prepare a fresh suspension before each drug intake.

Adults and children over the age of 14 years: 1 stol.l. (15 g) 3 times / day (45g).

Children under 5 years: 1 chayn.l. (5 g) 3 times / day (15 grams).

Children aged 5 to 14 years: 1 desert.l. (10 g) 3 times / day (30g).

In severe intoxication during the first three days, the dose can be doubled. The duration of treatment is 3-5 days.

In chronic intoxications and allergic conditions the duration of treatment is 2-3 weeks.

A second course - on doctor's advice.

Side effects:

From the digestive system: possible - nausea, constipation.

Other: with severe renal or hepatic insufficiency may cause feelings of disgust to the drug.

Contraindications:

• Intestinal atony
  
• Hypersensitivity to the drug.
  

Special instructions:

According to available data in the literature apply Enterosgel in the complex therapy of postpartum endometritis, obesity, bacterial vaginosis, inflammatory diseases of the uterus and appendages, with urogenital infections, cesarean section in the postoperative period. There are published data on the use of Enterosgel as a part of therapeutic measures in late gestosis and placental dysfunction.

The drug can be used in combination therapy with other drugs, subject to the rules in a separate reception time.

Overdose:

Data on overdose are not provided.

Drug Interactions:

In an application with Enterosgelem may decrease the absorption of other drugs.

Conditions and terms:

The drug should be stored out of reach of children at or below 4 ° C, do not freeze. Protect from drying out after opening the package. Shelf life - 3 years.