Expiration date: 02/2026
The composition and form of issue:
Tablets, enteric coated tablets, 1 tablet contains:
meglumine acridonacetates (in terms of greenexpo acid) 150 mg
auxiliary substances: povidone calcium stearate hypromellose Polysorbate 80 methacrylic acid and ethacrylate copolymer propylene glycol
in a contour acheikova packing 10 PCs in the paper cartons 1 or 5 packs.
Description pharmaceutical form:
The yellow tablets.
Pharmacokinetics:
With the introduction of the maximum permissible dose Cmax in plasma achieved through 2-3 h, gradually declining to 8 h after 24 h Cicloferon detected in trace amounts. T1/2 of the drug is 4-5 hours In recommended doses does not accumulates in the body.
Description pharmacological action:
Low-molecular inductor of interferon with a wide range of biological activities (antiviral, immunomodulating, anti-inflammatory, antiproliferative, antineoplastic etc.).
The drug induces high titers of alpha - and beta-interferon in organs and tissues, containing lymphoid elements (mucous of the small intestine, spleen, liver, lungs), passes the BBB.
Cycloferon is effective in the treatment of diseases caused by viruses of tick-borne encephalitis, flu, hepatitis, herpes, CMV, HIV, and various enteroviruses. Enhances the antibacterial effect of the antibiotics used in the treatment of acute intestinal infections. Has anticarcinogenic and antimetastatic effect, preventing the formation of tumors through the activation of immune defenses. Immunomodulatory effect of Cycloferon is expressed in the activation of phagocytosis, natural killer cells, cytotoxic T-lymphocytes and correction of immune status in immunodeficiency States of different origin.
Indications:
Adults (in the complex therapy):
- herpes infection
- acute intestinal infection
- chronic viral hepatitis B and C
- influenza and acute respiratory diseases
- of infection (serous meningitis, Lyme disease)
- HIV infection (AIDS stage 2A–2B)
- secondary immunodeficiency, associated with chronic bacterial and fungal infections.
In children, combination therapy, since 4 years:
- acute and chronic viral hepatitis B and C
- herpes infection
- prevention and treatment of influenza and acute respiratory infections
- acute intestinal infection
- HIV infection (stage 2A–2B).
Contraindications:
- hypersensitivity
- decompensated liver cirrhosis
- pregnancy
- breast-feeding
- age up to 4 years.
Side effects:
Allergic reactions.
Drug interactions:
Compatible with other drugs used in the treatment mentioned in the testimony of the diseases (interferons, chemotherapeutic drugs, etc.).
Method of application and dose:
Inside for 0.5 h before meals, not liquid.Adults:
Herpes infection — 4 table. to the 1, 2, 4, 6, 8, 11, 14, 17, 20 and 23 days. Course — 40 tab. The treatment begins with the first symptoms of the disease.
Flu and SARS — 4 table. at the reception on 1, 2, 4, 6, 8 day. The course is 20 table. Treatment should start at the first symptoms of infection. In severe course of the disease to the first visit accept 6 tabl. Additionally, symptomatic therapy (antipyretics, analgesics, expectorants).
Chronic viral hepatitis B and C — 4 tabl. to the 1, 2, 4, 6, 8, 11, 14, 17, 20 and 23 days of treatment further support for the scheme — 4 table. 1 every 3 days for 6 months. while maintaining the replicative and cytolytic activity up to 12 months. Recommended combination with interferons, antiviral drugs.
In the complex treatment of intestinal infections — 2 table. at the reception on 1, 2, 4, 6, 8 days and then 2 table. 11, 14, 17, 20, 23 days. The course is 20 table.
Neuroinfections — 4 table. to the 1, 2, 4, 6, 8, 11, 14, 17, 20 and 23 day further in supporting the scheme in table 4. at the reception 1 once in 3 days for 2.5 months. Course — 140 table.
HIV infection (stage 2A–2B) — 4 tabl. to the 1, 2, 4, 6, 8, 11, 14, 17, 20, 23 days, then maintenance treatment — 4 tabl. once in 3 to 5 days for 2.5 months. Course — 100-150 table. Repeated courses after 2-3 weeks after the previous.
Immunodeficiency States — 4 table. to the 1, 2, 4, 6, 8, continue treatment for 2 table. in the next 5 receptions on 11, 14, 17, 20, 23 day. The course is a 30 table.
The children aged 4-6 years — 150 mg (1 table.), at the age of 7-11 years — 300-400 mg (2-3 table). over 12 years in the 450-600 mg (3-4 tables). on reception of 1 times a day. A second course is advantageously carried out 2-3 weeks after the end of the first course.
Herpes infection is on 1, 2, 4, 6, 8, 11, 14 days of treatment. The course of treatment can vary depending on the severity of the condition and the severity of clinical symptoms.
In influenza and SARS — 1 time per day 1, 2, 4, 6, 8, 11, 14, 17, 20, 23 day and then 1 every 3 days. The course of treatment is 5-15 techniques depending on the severity of the condition and the severity of clinical symptoms.
Emergency nonspecific prevention of influenza and acute respiratory infections in the period of increasing incidence in these age doses 1, 2, 4, 6 and 8 days, then another 5 receptions with an interval of 72 h.
Chronic viral hepatitis b and/or C — at the indicated doses according to the scheme in 1, 2, 4, 6, 8, 10, 11, 14 day and then 1 every 3 days for 6 months while maintaining the replicative and cytolytic activity up to 12 months. Recommended combination with interferons, antiviral drugs.
HIV infection (AIDS stage 2A–2B) on the basic scheme 1, 2, 4, 6, 8, 10, 11, 14, 17, 20 days of therapy then 1 time per 3 days for 5 months.
Acute intestinal infections — 1, 2, 4, 6, 8, 11, 17, 20 days of treatment 1 time per day. Rate — 6-18 table.
Precautions:
In diseases of the thyroid treatment should be under the control of the endocrinologist.
