• Combipec (Salbutamol theophylline)

Expiration date: 05/2022

Structure and Composition

Combipec tablets prolonged action

1 tablet contains salbutamol 6, 8 or 10 mg, 200 mg of theophylline, in multiples of 50 pcs.

Pharmachologic effect

The structure and action close to salbutamol other beta2-agonists. It has bronhorasshiryayushee and tocolytic (uterine muscle relaxant) effect. In therapeutic doses does not usually cause tachycardia (rapid heart rate) and blood pressure changes.


Apply with bronchial asthma and other respiratory diseases that occur with spastic states (narrowing of the lumen) of the bronchi.


Hypersensitivity, pregnancy (when used as a bronchodilator), breastfeeding, children under 2 years.

Dosing and Administration

Dosage is determined individually.

Side effects

From the nervous system and sensory organs: tremor (usually hands), anxiety, tension, irritability, dizziness, headache, insomnia, intermittent convulsions.

Cardio-vascular system and blood (blood, hemostasis): palpitations, tachycardia (during pregnancy - the mother and fetus), arrhythmias, peripheral vascular expansion, reduction or increase Sad Dad, myocardial ischemia, heart failure, cardiomyopathy.

From the digestive tract: nausea, vomiting, dryness or irritation in the mouth or throat, loss of appetite.

Other: bronchospasm (paradoxical or caused by hypersensitivity to salbutamol), throat, difficulty urinating, sweating, increased blood glucose, free fatty acids, hypokalemia (dose-dependent), allergic reactions such as erythema, edema of the face, difficulty breathing, development of physical and mental drug dependence.

Drug interactions

Increases the activity of the central nervous system stimulants, kardiotropnyh thyroid hormones. Ephedrine and theophylline potentiate toxic effects. Corticosteroids, PG synthesis inhibitors, tricyclic antidepressants and MAO blockers increase the risk of cardiovascular events, means for inhalation anesthesia and levodopa - severe ventricular arrhythmias.