Expiration date: 04/2026
The composition and form of issue
The coated tablets: 1 tablet contains piracetam 200, 400, 800 mg
20, 30, 60 PCs.
Pharmacological action:
Piracetam is nootropic agent. Has a positive effect on brain metabolism: it increases the concentration of ATP in the brain tissue, enhances the synthesis of RNA and phospholipids, stimulates glycolytic processes, enhances glucose utilization. Improves integrative brain activity, promotes memory consolidation, eases the process of learning. Changes the velocity of propagation of excitation in the brain, improves microcirculation, without vasodilating action, inhibits the aggregation of activated platelets. Has a protective effect in brain damage caused by hypoxia, intoxication, an electric shock, increases the alpha - and beta-activity, reduces Delta activity on EEG, reduces the severity of vestibular nystagmus. Improves communication between the cerebral hemispheres and the synaptic conductance in neokorticalnah structures, improves mental performance, improves cerebral blood flow. The effect develops gradually, Almost does not have a sedative and stimulating effect.
Testimony
Piracetam is used in neurological, psychiatric and substance abuse treatment.
In neurological practice, piracetam is used mainly by vascular brain diseases (atherosclerosis, hypertension, vascular parkinsonism) with symptoms of chronic Cerebro-vascular insufficiency, which manifests itself in impaired memory, attention, speech, dizziness and headache, disorders of cerebral circulation and subcomittee and comatose States after injuries and intoxication of the brain, as well as during rehabilitation therapy after these States with the aim of improving motor and mental activity of patients. Piracetam is also used in patients with diseases of the nervous system, accompanied by a decline in intellectual-mnestic functions and disorders of emotional-volitional sphere.
In psychiatric practice used piracetam in patients with neurotic depressive States of different Genesis with a predominance in the clinical picture signs of weakness, asthenic and sinesto-hypochondriacal disorders, phenomena ideatornoy retardation, as well as in the therapy sluggish-apathetic defective conditions, senile and atrophic processes in the complex therapy of mental illness occurring in "organically inferior soil." In addition, piracetam is used as an aid in the treatment of depression resistant to antidepressants, as well as when poor tolerability of antipsychotics and other psychotropic drugs to eliminate or prevent caused their somatic vegetative, neurological or mental complications. As a subsidiary means piracetam can be used in epilepsy.
In substance abuse treatment the drug is used as a means of relief of withdrawal symptoms, pre - and delirious States in alcoholism and addictions, as well as in cases of acute alcohol poisoning, morphine, barbiturates, amphetamine, etc. in addition, piracetam is used in the treatment of chronic alcoholism with symptoms of persistent disorders of mental activity (asthenia, intellectual-mental disorders, etc.).
The testimony of the children. If you need to speed up the learning process and to eliminate the effects of perinatal brain damage caused by intrauterine infections, hypoxia, birth trauma, mental retardation, mental retardation, cerebral palsy.
Contraindications
Severe renal insufficiency (if creatinine clearance less than 20 ml/min), pregnancy, lactation (breastfeeding), hypersensitivity to the drug.
Method of application and doses
Adult ingestion dose is 30-160 mg/kg in 2-4 doses. Duration of treatment - 6-8 weeks.
For children the ingestion dose is 30-50 mg/kg/day in 2-3 reception. Treatment should continue for at least 3 weeks.
Pills Piracetam usually taken orally before meals.
Piracetam is administered intramuscularly or intravenously, starting with 2-4 g, quickly bringing a dose of 4-6 grams per day. After improvement, reduce dose and go on to the reception inside - 1, 2-1, 6 g (0, 4 g 3-4 times a day).
Older patients with long-term therapy appoint Piracetam at a daily dose of 4.8 g for several weeks, and then prescribe a maintenance dose is 1.2-1.4 g/day.
If necessary, use the/m or/in a dose of 10 g/day. At/in the introduction patients in serious condition, the daily dose may be 12 g. After clinical improvement the dose is gradually reduced and go to the reception inside.
Side effects
From the digestive system: rarely - dyspepsia, abdominal pain.
CNS: rarely - nervousness, agitation, irritability, anxiety, sleep disorders, dizziness, headache, tremor, in some cases, weakness, drowsiness.
Other: increased sexual activity.
Special instructions:
Patients with impaired renal function history of the drug is administered with caution these patients require correction of dosing regimen based on the values of creatinine clearance.
In the case of sleep disorders is recommended to cancel an evening reception of the drug, attaching the dose to day reception.
Piracetam penetrates through the filter membrane devices for hemodialysis.
Use caution when working with machinery.
Drug interactions
Increases the effectiveness of thyroid hormones, antipsychotic drugs (neuroleptics), indirect anticoagulants (in the background of high doses of piracetam), psychostimulants.
In the appointment with neuroleptics reduces the risk of extrapyramidal disorders.
Storage conditions
In a dry, protected from light. Store in places inaccessible to children.
