Expiration date: 11/2025
The composition and form of issue:
Solution for intravenous and intramuscular injection, 1 ampoule contains:
diclofenac sodium 75 mg
excipients: mannitol benzyl alcohol sodium hydroxide sodium metabisulfite propylene glycol water for injections
in ampoules of 3 ml in a box 5 ampoules.
Tablets, film-coated, prolonged action, 1 tablet contains:
diclofenac sodium 100 mg
excipients:
core — sucrose cetyl alcohol silica colloidal anhydrous magnesium stearate polyvidone
shell — gidroximetilpropilzelluloza iron oxide red (E172) Polysorbate talc titanium dioxide polyethylene glycol sucrose
blistere in 10 PCs., in box 2 blisters.
Description pharmaceutical form:
Solution: clear solution from colorless to light yellow color with a faint odor of benzyl alcohol.
Tablets: tablets, film-coated, pink, round, uniform and smooth surface, with beveled edges. Kind of in the break: the kernel is white.
Method of application and dose:
Solution for injection: in/m or/in, drip in the form of infusion. Is introduced not more than 2 days. In case of prolongation of treatment, patients prescribed a drug in the form of tablets or suppositories.
Intramuscular injection: for acute pain — 75 mg daily, if necessary (biliary or renal colic) the daily dose may be increased to 150 mg (1 ampoule 2 times a day).
Intravenous infusion: the drug is administered in the form of drip infusions. Immediately before administration the contents of 1 ampoule (75 mg) should be diluted in 100-500 ml 0, 9% NaCl solution or 5% dextrose solution (after adding to infusion solutions solution of sodium bicarbonate — 0, 5 ml of 8, 4% 1 or 4 ml, 2% solution). The prepared solutions for infusion should be transparent.
In the treatment of postoperative pain syndrome of average and severe degree of severity of the drug is administered at a dose of 75 mg for 30-120 min. If necessary, the drug can be administered again after a few hours. However, the dose should not exceed 150 mg over a period of 24 hours.
To prevent postoperative pain, spend an infusion of "shock" dose of 25-50 mg over 15-60 min. In the future, continue infusion at 5 mg/h until the maximum daily dose of 150 mg.
Extended-release tablets: inside, not liquid, squeezed small amounts of water, usually during or after a meal. Appoint 1 table. (extended-release tablets 100 mg) 1 times a day if necessary daily dose increased to 150 mg, optionally assigning 1 a conventional tablet containing 50 mg of diclofenac.
