Expiration date: 05/2026

Release form, composition and packaging 

Tablets, film-coated from light yellow-orange to dark orange in colour, oval, lenticular; it allowed the presence of a specific smell.

1 tablet contains:

chondroitin sulfate sodium 400 mg

glucosamine hydrochloride 500 mg

methylsulfonylmethane 300 mg

sodium hyaluronate (in terms of hyaluronic acid) 10 mg

Excipients: cellulose microcrystalline 199.4 mg, calcium hydrogen phosphate dihydrate 116.9 mg, stearic acid 48 mg, croscarmellose sodium 50 mg, magnesium stearate 10 mg colloidal silicon dioxide 4 mg.

The composition of the film shell: Opadry II orange (17.56 mg hypromellose, Polydextrose 7.92 mg, colorant titanium dioxide (E171) 0.44 mg, talc 7.88 mg, maltodextrin 4.68 mg, triglycerides of medium chain length 0.6 ppm, dye sunset yellow aluminum lacquer (E110) 0.92 mg) 40 mg.

Clinico-pharmacological group: Drug that stimulates the regeneration of cartilage tissue, the anti-inflammatory effect

Pharmaco-therapeutic group: tissue Regeneration stimulator

Testimony

• osteoarthritis of the peripheral joints;
  
• osteochondrosis of the spine.
  

The dosage regimen

Inside. Adults and children over 15 years: 1 tablet 2 times a day during the first three weeks; 1 tablet 1 time per day during the subsequent weeks and months. The course of treatment at least 3 months

Side effects

• allergic reactions;
  
• epigastric pain, flatulence, diarrhea, constipation, nausea, vomiting.
  

Contraindications

• pregnancy, lactation;
  
• children up to age 15 years;
  
• hypersensitivity to the drug.
  

Caution: bleeding disorders, diabetes, bronchial asthma, intolerance to seafood (shrimp, clams).

Application of pregnancy and breastfeeding

Contraindicated in pregnancy and lactation.

The children

Contraindicated in children up to 15 years.

Special instructions

Not recommended for children under 15 years due to the lack of scientific data for this category of patients.

Effects on ability to drive vehicles and management mechanisms

Has no effect on driving and operating other mechanisms.

Overdose

Cases of overdose are not known. In the case of receiving large amounts of drug (10 capsules) may cause nausea, vomiting, diarrhea, hemorrhagic rash. Symptomatic treatment: gastric lavage.

Drug interactions

Increases removals tetracycline, reduces the effects of semisynthetic penicillins. The product is compatible with the NSAIDs (nonsteroidal anti-inflammatory drugs) and corticosteroids (glucocorticoids). May increase the action of indirect anticoagulants, antiplatelet agents, fibrinolytics.