Expiration date: 05/2025
Structure and Composition
Dimia tablets, film-coated
1 tab. contains 20 mcg ethinyl estradiol, drospirenone 3 mg, in the packing 28 pcs.
Pharmachologic effect:
The drug Dimia is a combined monophasic oral contraceptive containing drospirenone and ethinyl estradiol. According to their pharmacological profile of drospirenone similar to the natural progesterone: it does not have estrogenic, glucocorticoid and antiglucocorticoid activity and is characterized by a pronounced anti-androgenic and mild antimineralokortikoidnym action. The contraceptive effect is based on the interaction of various factors, the most important of which are the inhibition of ovulation, increasing the viscosity of cervical secretions and the change of the endometrium. Pearl Index, an indicator of the rate of pregnancy in 100 women of childbearing age during the year of application of the contraceptive is less than 1.
Testimony:
Oral contraception.
Contraindications:
Hypersensitivity
thrombosis (venous and arterial) present or in history (including deep vein thrombosis, pulmonary embolism, myocardial infarction, cerebrovascular accident), the state prior to thrombosis (including transient ischemic attack, angina pectoris) in current and history,
diabetes with vascular complications,
presence of severe or multiple risk factors for venous or arterial thrombosis, including complicated lesion valvular atrial fibrillation, cerebrovascular disease, or coronary artery disease,
uncontrolled hypertension, major surgery with prolonged immobilization, smoking at the age of 35 years,
liver failure, severe liver disease (up to normalization of "liver" tests) in the current or a history of liver tumors (benign or malignant), including: a history
severe or acute renal failure, hormone-dependent malignant diseases of the genital organs or the breasts or suspicion on them, vaginal bleeding of unknown origin, pregnancy or suspicion of her lactation.
Carefully.
Risk factors for thrombosis and thromboembolism:
smoking, obesity, dislipoproteinemia, hypertension, migraine, valvular disease, prolonged immobilization, major surgery, major trauma, genetic predisposition to thrombosis (thrombosis, myocardial infarction or cerebrovascular accident at a young age in any of the next of kin),
diseases for which may occur peripheral circulatory disorders: diabetes, lupus, hemolytic uremic syndrome, Crohn's disease, ulcerative colitis, sickle cell anemia, phlebitis of superficial veins, hereditary angioedema, hypertriglyceridemia, liver disease,
the disease first appeared or worsen during pregnancy, or on the background of the previous use of sex hormones (including jaundice and / or pruritus related to cholestasis, cholelithiasis, otosclerosis with hearing impairment, porphyria, herpes gestationis, chorea (Sydenham's disease) , Sydenham's chorea, chloasma), the postpartum period.
Dosing and Administration
Inside, the tablet 1, in the order indicated on the package, every day at about the same time with a small amount of water, continuously for 21 days. Reception following each package begins after a 7-day break, during which there menstrualnopodobnoe bleeding. It usually starts on day 2-3 by taking the last tablet and may not end before you start taking a new package.
Without taking any hormonal contraceptive use in the preceding month, the drug begins on the first day of the menstrual cycle (first day of menstrual bleeding). Shall start receiving 2-5 days of the menstrual cycle, but in this case it is recommended to additionally use a barrier method of contraception during the first 7 days of tablet-taking from the first package.
In the transition from receiving others. COCs preferably start taking the drug the next day after taking the last active tablet of the previous package, but not later than the day after the usual 7-day break in the reception (for products containing 21 tablets), or after the last inactive pills (for products containing 28 tablets per pack).
When switching from contraceptives containing only progestin (mini-pill, injectable form, implant): a mini-pill can go any day (without a break), with the implant - the date of its removal from the injection mold - from the day when should following injection was to be made. In all cases, you must use an additional barrier method of contraception during the first 7 days of taking the pills.
After the abortion I trimester of pregnancy, you can start taking immediately. Under this condition there is no need for additional contraceptive protection.
After delivery or abortion in the II trimester of pregnancy is recommended to start taking the drug in the 21-28 day. If the reception is started later, you must use an additional barrier method of contraception during the first 7 days of taking the pills. In the case of sexual intercourse before you start taking the drug should be excluded pregnant or you must wait for the first menstrual period.
Receiving Missed tablets: If the delay in receiving the tablet is less than 12 hours, contraceptive protection is not reduced. It is necessary to take a pill as soon as possible, should be taken at the usual time.
If the delay in receiving the tablets was more than 12 hours (the interval since last receiving tablets over 36 hours), contraceptive protection can be reduced. When you miss 1-2 weeks taking the drug need to take the last missed tablet as soon as possible (even if it means taking 2 tablets at the same time). The next tablet is taken at the usual time. In addition to be used a barrier method of contraception for the next 7 days. If intercourse took place during 1 week before skipping pills, you need to take into account the chance of pregnancy. The more missed tablets and the closer this pass to the 7-day break in taking the drug, the greater the risk of pregnancy.
In the case of missing 3 weeks taking the drug, you should take the last missed tablet as soon as possible (even if it means taking 2 tablets at the same time). The next tablet is taken at the usual time. In addition to be used a barrier method of contraception for the next 7 days. Furthermore, pills from a new package to be started as soon as the current package, i.e. nonstop. Most likely, the bleeding "cancel" will not be until the end of the second pack, but there may be "smearing" bleeding or uterine bleeding "cancel" in the days of the drug in the second package.
When you miss a tablet-and the absence of the first administration of the drug-free interval of bleeding "cancel" it is necessary to exclude pregnancy.
In the event of missed doses can be guided by the following two basic rules: the drug should never be interrupted for more than 7 days, 7 days of continuous reception of tablets required to achieve adequate suppression of the hypothalamic-pituitary-ovarian system.
If vomiting and diarrhea within 3-4 hours after administration of the tablet may be incomplete absorption. In this case, you must abide by the rules of the drug in case of missing tablets. If the patient does not want to change the normal dose, it must take, if necessary, an additional tablet (or more tablets) of others. Packaging.
To delay the date of the onset of menstruation should continue taking pills from a new pack immediately after taking all the tablets from the previous one, without a break in the reception. Tablets of the new package can take as long as possible until the package is completed. Against the background of the drug from the second package may be marked "smearing" bloody discharge from the vagina or uterine bleeding "breakthrough." Reactivate the drug from a new package follows the usual 7-day break.
To move the date of the beginning of menstruation to others. Day of the week should be shortened next tablet-free interval for as many days as necessary to postpone the beginning of menstruation. The shorter the interval, the higher the risk of bleeding, "cancel" and as the "smearing" emissions and "breakthrough" bleeding while taking second pack (just as in the case of delay the onset of menstruation).
