Expiration date: 02/2025

Structure and Composition:

Vaginal Suppositories. 1 suppositorie contains:

benzalkonium chloride 18.9 mg

Other ingredients: hard fat (Witepsol) - a sufficient amount to obtain a suppository weighing 1.75 g

in blisters 5 pcs. 2 In the paper cartons packaging.

Description pharmaceutical form:

Suppositories from white to white with a yellowish shade, Valium forms.

Pharmacokinetics:

Almost not absorbed when administered vaginally, simple cleaning the water is removed and normal physiological secretions.

Description of the pharmacological actions:

Local contraceptive (spermicidal) tool, also has antiseptic, antifungal, antiprotozoal action inactivates the virus Herpes simplex.

It shows bactericidal activity against staphylococci, streptococci, gram-negative bacteria (Escherichia coli and Pseudomonas sticks, Neisseria gonorrhoeae, Proteus, Klebsiella and others.), Anaerobic bacteria, fungi and molds. Acts on strains of bacteria resistant to antibiotics and other chemotherapeutic drugs inhibit hyaluronidase plazmokoagulazu and staphylococci.

Spermicidal effect is due to the ability to damage the sperm membrane (first - flagellum, then - head), resulting in the impossibility of damaged sperm fertilization. The effect is a 5 min after the administration of a vaginal suppository.

It is active in the prevention of diseases, sexually transmitted diseases (gonorrhea, chlamydia, trichomoniasis). It does not affect the normal vaginal flora (including on the stick Doderlyayna) and hormonal cycle.

Indications:

Local contraception for women of reproductive age, incl .:

• contraindications to the use of oral contraceptives or intrauterine contraception
  
• postpartum, lactation
  
• post-abortion
  
• premenopauznom period
  
• need occasional protection against pregnancy
  
• omission or delay in receiving consistently used oral contraceptives.
  

Contraindications:

• Hypersensitivity to the drug
  
• coleitis, ulceration and irritation of the mucous membrane of the vagina and uterus.
  

Application of pregnancy and breastfeeding:

Accidental use of the drug during pregnancy, adverse effects on the fetus during pregnancy, and does not render. Not excreted in breast milk, may be used during lactation.

Side effect:

Allergic reactions.

Drug Interactions:

Any drug introduced vaginally may reduce local spermicidal effect (including soap and solutions containing it).

iodine solution (including 0.1% solution yodonata) inactivate the drug.

Dosage and administration:

Vaginally. Pre-releasing suppository of contour packaging, is introduced deep into the vagina in the supine position, at least 5 minutes prior to sexual intercourse duration -. 4 hours, single dose - 1 suppository 1 intercourse. Be sure to enter a new vaginal suppository in the case of repeated sexual acts. Multiplicity use limited individual tolerability of the active substance and the frequency of sexual intercourse.

Special instructions:

To improve efficiency, careful adherence to a method of using the drug. Can be used in conjunction with vaginal diaphragm or intrauterine contraception.

After sexual intercourse in order to avoid loss of contraceptive effect is not suitable for intravaginal use hygiene products (douching with soapy water, because the soap breaks down the active drug substance) is possible External toilet genitals.