Expiration date: 10/2026

Structure and Composition: 

Eye drops 0.25 ml of 1%

timolol maleate 3.42 mg

(Corresponds to 2.5 mg of timolol)

Excipients: Benzalkonium chloride - 0.03 mg (as a preservative), disodium edetate dihydrate povidone monosodium phosphate dihydrate Sodium monohydrogen phosphate dodecahydrate water for injection

in vials-droppers of 5 ml in box of 1 vial.

0.5% eye drops 1 ml

timolol maleate 6.83 mg

(Corresponding to 5 mg timolol)

Excipients: Benzalkonium chloride - 0.03 mg (as a preservative), disodium edetate dihydrate povidone monosodium phosphate dihydrate Sodium monohydrogen phosphate dodecahydrate water for injection

in vials-droppers of 5 ml in box of 1 vial.

Pharmachologic effect:

Beta-adrenoceptor blocking and reduces the secretion of aqueous humor, reducing the intraocular pressure.

Pharmacokinetics:

Well absorbed by the retina and the nasal mucosa, it is excreted in the urine.

Clinical Pharmacology:

In topical application the intraocular pressure decreases after 20 minutes, the maximum effect - in 2-3 hours duration - 24 hours.

Indications:

Glaucoma (all forms).

Contraindications:

Hypersensitivity, severe obstructive airways disease, sinus bradycardia, AV block, heart failure, severe allergic rhinitis.

Application of pregnancy and breastfeeding:

When used in the I trimester of pregnancy must be weighed the possible benefits and potential risk.

Side effect:

Nausea, diarrhea, weakness and fatigue, disorientation, hallucinations, respiratory failure, bradyarrhythmia, hypotension, bronchospasm, reduction of tear secretion, blepharitis, conjunctivitis, keratitis, allergic reactions, tachyphylaxis.

Drug Interactions:

Compatible with miotocs and carbonic anhydrase inhibitors.

Dosage and administration:

At the beginning of therapy instilled 1 drop preparation Arutimol 0.25 or 0.5% in the diseased eye two times a day.

If the intraocular pressure is normal with regular use, the dosage should be limited to 1 times daily 1 drop of the drug.

Arutimolom treatment is carried out, as a rule, for a long time. Suspension or dosage change be made only by order of the physician.

Shelf life:

After opening the vial 6 weeks.

Arutimol
(Timolol)
eye
drops