Expiration date: 01/20262
Structure and Composition:
Benzylpenicillin sodium salt crystal. 1 vial of powder for solution for injection contains benzylpenicillin sodium 1,000,000 IU.
Benzylpenicillin novocaine salt. 1 vial of powder for solution for injection - procaine penicillin G 600,000 units (in a box of 10 or 50 bottles).
Dosage and administration:
Benzylpenicillin sodium salt crystal. V / m, n / a, or intracisternally.
When i / m administration of a single dose for adults - 250000-500000 IU daily - 1-2 million units (the maximum daily dose, if necessary - 40-60 million units). The daily dose for children: up to 1 year - 50000-100000 U / kg, over 1 year - 50,000 units / kg (in severe infections the daily dose increased to 200000-300000 units / kg, for health reasons - to 500,000 IU / kg). For the / m of solution is prepared immediately prior to administration, adding to the contents of the vial 1-3 ml of water for injection or 0.9% sodium chloride solution or 0.25 - 0.5% solution of novocaine.
P / for injecting infiltrates - 100000-200000 units in 1 ml of 0.25-0.5% solution of novocaine. The duration of treatment and the intervals between doses are set by your doctor.
Benzylpenicillin novocaine salt. V / m deep (in / or prohibited to enter endolyumbalno). The average therapeutic dose for adults: single - 300,000 IU daily - 600,000 units. The maximum daily dose for adults - 1.2 million units. Children under one year of age appoint 50000-100000 U / kg / day over 1 year - 50,000 units / kg / day. Multiplicity of 1-2 times a day. Solutions are ex tempore, adding to the contents of the vial 2-4 ml of water for injection or isotonic sodium chloride solution. The contents of the vial shaken vigorously, the resulting suspension was quickly drawn into a syringe for injection is recommended to use a needle of 0.8 mm.
The duration of treatment depends benzylpenicillin From the form and severity of the disease - from 7-10 days to 2 months or more (bacterial endocarditis, septicemia). In the absence of clinical effect 3-5 days after initiation of treatment are switching to treatment with other antibiotics or combinations with aminoglycosides (streptomycin, kanamycin, gentamicin) and penitsillinazoustoychivymi penicillins (oxacillin).