Expiration date: 04/2027

Capsules 300mg 

Pharmacological group: Various anticonvulsant and antispastic agents

Composition

The active ingredient - gabapentin.

Pharmachologic effect

Anticonvulsant, analgesic effect. Gabapentin does not undergo significant metabolism in humans. Food intake has little effect on the rate and extent of absorption of gabapentin. Penetrates into breast milk when taken orally. Displayed by renal excretion. The half-life is 5-7 hours and is independent of dose and multiple dose subsequent doses.

Indications

Gabapentin is indicated for partial seizures with or without secondary generalization in adults and children older than 12 years (as an adjunct), partial seizures in children 3-12 years of age (as a further means), as well as for the treatment of post-herpetic neuralgia in adults.

Contraindications

Hypersensitivity, children up to 3 years with partial seizures and 12 years post-herpetic neuralgia, breastfeeding.

Side effect

In the treatment of postherpetic neuralgia.

On the part of the body as a whole: asthenia, back pain, headache, infection, abdominal pain, peripheral edema, weight gain, hyperglycemia.

From the digestive system: constipation, diarrhea, dry mouth, dyspepsia, flatulence, nausea, vomiting.

From the central and peripheral nervous system: violation of gait, coordination, amnesia, ataxia, dizziness, hypesthesia, somnolence, abnormal thinking, tremor.

The respiratory system: dyspnea, pharyngitis,

Dermatological reactions: rash.

From the senses: amblyopia, conjunctivitis, diplopia, otitis media.

In the treatment of epilepsy.

On the part of the body as a whole: asthenia, malaise, face edema, fatigue, fever, headache, viral infection, peripheral edema, weight gain.

Cardio-vascular system: vasodilation.

From the digestive system: constipation, loss of teeth, dyspepsia, increased appetite, dry mouth or throat.

Hematopoietic system: leukopenia.

From the Musculoskeletal System: arthralgia, back pain, fractures, myalgia.

From the central and peripheral nervous system: dizziness, anxiety, hostility, amnesia, ataxia, confusion, incoordination, hyperkinesia, depression, dysarthria, insomnia, nervousness, nystagmus, drowsiness, abnormal thinking, tremor, convulsions.

The respiratory system: cough, pharyngitis, rhinitis.

Dermatological reactions: abrasions, skin itching, skin rash.

From the urinary system: urinary tract infection, impotence.

From the senses: blurred vision, amblyopia, diplopia.

Interaction

Antacids reduce the bioavailability of gabapentin. Cimetidine significantly reduces the excretion of gabapentin.

Overdose

Symptoms: double vision, slurred speech, drowsiness, lethargy, diarrhea.

Treatment: supportive therapy, hemodialysis.

special instructions

Pregnancy is possible if the expected effect of therapy outweighs the risk to the fetus. When co-administered with morphine is necessary to strictly control the side effects arising from the CNS. The dose of gabapentin and morphine reduced gradually. Gabapentin should be taken no earlier than 2 hours after taking an antacid. Gabapentin should not be used in patients up to 12 years with impaired renal function. Be wary appoint older. While receiving gabapentin should not drive vehicles and to use sophisticated technology that requires high concentration of attention.

Storage conditions

Store at temperatures not above 25 ° C.