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Expiration date: 01/2027

Structure and Composition:

Powder for solution for injection.

active substance per 1 vial: galavit 50 mor 100 mg

in bottles of 5 or 10 ml in a cardboard pack of 5 bottles.

Suppositories for rectal administration.

active substance per 1 suppository: galavit 50 or 100 mg

Other ingredients: Witepsol Witepsol H15 W35

in blisters 5 pcs. a stack of cardboard packaging 1 or 2.

Tablets for sublingual.

active substance per 1 tablet: galavit 25 mg

Excipients: sorbitol starch, lactose, calcium stearate, talc ratsementol (menthol)

in blisters of 10 or 20 pieces. In the paper cartons 1, 2, 3 and 4 in the group packing packing 10, 20, 30, 40 and 50 packs.

Description pharmaceutical form:

Crystalline powder: white or white with a yellowish tinge.

Suppositories: from white to white with a yellowish shade, Valium forms without visible inclusions in the longitudinal section.

Tablets: white with a yellowish tinge, lenticular, without risks, with the smell of menthol.

Pharmacokinetics:

Report from the body by the kidneys. After the / m injections T1 / 2 - 30-40 minutes after rectal administration - 40-60 minutes after sublingual - 30 min. The main pharmacological effects are observed for 72 hours.

Description of the pharmacological actions:

It has an effect on functional and metabolic activity of macrophages. In inflammatory diseases of the reversible 6-8 hours inhibits excessive synthesis of tumor necrosis factor, IL-1 and other pro-inflammatory cytokines, reactive oxygen species giperaktivirovannymi macrophages, determining the degree of inflammatory reactions, their recurrence, as well as the severity of intoxication. The normalization of the functional state of macrophages leads to the restoration of antigen-presenting and controlling functions, reduce the level of self-aggression.

It stimulates the bactericidal activity of neutrophils, enhancing phagocytosis and increasing non-specific resistance of the organism to infectious diseases.

Testimony:

As an immunomodulatory and anti-inflammatory agent in the treatment of adults and adolescents from 12 years of age (in / m injections, suppositories, tablets):

  • frequent recurrent disease of the respiratory tract and upper respiratory tract bacterial and viral (influenza, frequent acute respiratory viral infections, bronchitis, pneumonia, chronic tonsillitis, chronic otitis media, chronic adenoids) and their prevention
  • gastric ulcer and duodenal ulcer
  • viral hepatitis
  • chronic recurrent disease caused by the herpes virus
  • diseases caused by papilloma virus
  • infectious and inflammatory urogenital diseases (chlamydial urethritis and trichomonas etiology, chlamydial prostatitis, acute and chronic oophoritis, endometritis)
  • pyo-inflammatory diseases of the pelvic organs, postoperative rehabilitation of patients with uterine myoma postoperative complications in women of reproductive age
  • postoperative pyo-septic complications and their prevention (including cancer patients)
  • chronic recurrent furunculosis, erysipelas
  • asthenic conditions, neurotic and somatoform disorders, decreased physical performance (including the athletes)
  • mental, behavioral and postabstinentnom disorders in alcohol and drug addiction
  • inflammatory diseases of the oral mucosa and throat, periodontal disease.
  • In monotherapy in adults and adolescents from 12 years of age (in / m injection):
  • acute and chronic infectious and inflammatory diseases of the gastrointestinal tract, accompanied by intoxication and / or diarrhea
  • chronic urogenital infections, including during immunoreabilitatsionnyh activities interrecurrent period in order to maintain clinical remission.

As immunomodulating and anti-inflammatory agent in the treatment of children 6-11 years old (i / m injections and suppositories):

  • prevention of influenza and acute respiratory infections
  • Infectious intestinal diseases accompanied by intoxication and / or diarrhea
  • gastric ulcer and duodenal ulcer
  • viral hepatitis
  • chronic recurrent disease caused by the herpes virus
  • diseases caused by papilloma virus
  • asthenic conditions, neurotic and somatoform disorders, decreased physical performance
  • postoperative pyo-septic complications and their prevention (including cancer patients)
  • treatment and prevention of urogenital infections of bacterial and viral aetiology
  • inflammatory diseases of the oral mucosa and throat, periodontal disease
  • purulent surgical diseases (burn lesions, recurrent furunculosis, chronic osteomyelitis, gangrenous appendicitis with omentitom, peritonitis, purulent pleurisy)
  • frequent recurrent disease of the respiratory tract and upper respiratory tract bacterial and viral aetiology (frequent acute respiratory viral infections, bronchitis, pneumonia, chronic tonsillitis, chronic otitis media, chronic adenoids).

Contraindications:

  • idiosyncrasy
  • pregnancy
  • lactation.

Application of pregnancy and breastfeeding:

Contraindicated during pregnancy. At the time of treatment should stop breastfeeding.

Side effect:

Allergic reactions are possible.

Drug Interactions:

In an application may reduce the dose courses of antibiotics. Cases not marked incompatibility with other drugs.

Dosage and administration:

V / m, rectally, sublingually.

V / M: content of the vial prior to administration diluted in 2 ml of water for injection or 0.9% sodium chloride solution. Dose and duration of administration depends on the nature, severity and duration of the disease. Dosage for adults and adolescents from 12 years - 100 mg, for children 6-12 years - 50 mg.

In gastric ulcer and duodenal ulcer in the acute period of 2 days at 200 mg 1 time per day, followed by 100 mg every 72 hours course - 20-25 injections.. In chronic period - 5 days of 100 mg 1 time per day, followed by 100 mg every 72 hours course -. 20 injections.

When viral hepatitis: the initial dose - 200 mg dose, followed by 100 mg 2 times a day until relief of symptoms of intoxication and inflammation. The subsequent continuation of the course - 100 mg every 72 hours course -. 20-25 injections.

In chronic recurrent diseases caused by herpes virus - 100 mg daily for 5 injections and then 100 mg every other day injections of 15.

In diseases caused by papilloma virus, - 5 days on 100 mg once in one day, followed by 100 mg every other day. Course - 20 injections.

When urogenital diseases - chlamydia and trichomonas urethritis etiology, chlamydial prostatitis: 1 day 100 mg twice, then 100 mg every other day. Rate - 10-15 injections (depending on the severity of a pathological process).

When oophoritis, endometritis: in the acute period - 2 days 200 mg 1 time per day, followed by 100 mg every 72 hours in the chronic period - 5 days of 100 mg 1 time per day, followed by 100 mg every 72 hours. . course - 20 injections.

In acute and chronic septic diseases of the pelvic organs: in the acute period - 1 day 200 mg once daily, 3 days at 100 mg daily, followed by 100 mg every other day for 5 injections. Course - 10 injections. In chronic period - 5 days of 100 mg 1 time a day, then 100 mg every 72 hours course -. 20 injections.

For post-operative rehabilitation of patients with uterine fibroids and postoperative complications in women of reproductive age: 5 days of 100 mg 1 time per day, followed by 100 mg every other day. Course - 20 injections.

For the prevention and treatment of surgical complications in the pre- and postoperative period (including cancer patients) administered 100 mg 1 time per day, 5 injection before surgery, after surgery 5 injections of 100 mg in a day and 5 to 100 mg injection with an interval of 72 hours in severe disease the initial dose -. 200 mg once daily or 2 times a day 100 mg. Course - 20 injections.

In chronic recurrent furunculosis, erysipelas: 5 days of 100 mg 1 time per day, followed by 100 mg every other day. Course - 20 injections.

When asthenic conditions, neurotic and somatoform disorders, with mental, behavioral and postabstinent disorders in patients with alcohol and drug dependence: 5 days at 100 mg daily, then 100 mg every 72 hours course - 15-20 injections..

To improve the physical performance: 100 mg every other day injections of 5, then 100 mg every 72 hours, rate - 20 injections.

In inflammatory diseases of the mucous membranes of the mouth and throat, periodontal diseases: the initial dose - 100 mg daily to 5 injections, followed by 100 mg every 72 hours course - 20 injections..

V / m in adults and adolescents 12 years as monotherapy

In acute and chronic infectious and inflammatory diseases of the gastrointestinal tract, accompanied by intoxication and / or diarrhea, - 200 mg dose, followed by 100 mg 2 times a day until relief of symptoms of intoxication. Perhaps the subsequent continuation of the course of 100 mg every 72 hours course -. 20-25 injections.

In chronic urogenital infections, including during immunoreabilitatsionnyh activities interrecurrent period in order to maintain clinical remission: 100 mg every other day course of 10 injections.

V / m in children older than 6 years

When purulent surgical diseases (burn lesions, recurrent furunculosis, chronic osteomyelitis, gangrenous appendicitis with omentitom, peritonitis, purulent pleurisy): children from 6 to 11 years - 1 injection of 50 mg per day - 5 days, followed by one injection of 50 mg every other day for 10-15 days. The course - 10-15 injections to children aged 12-18 years - the treatment is carried out in the same manner as in / m to 100 mg injections. When dressings desirable galavita topical application in the form of bandages with sterile cloth dampened with a solution of 1% galavita in water for injection (in bandages with mash or water-soluble ointment dressings).

With frequent recurrent respiratory diseases and upper respiratory tract bacterial and viral aetiology (frequent acute respiratory viral infections, bronchitis, pneumonia, chronic tonsillitis, chronic otitis media, chronic adenoids): children from 6 to 11 years - 1 injection of 50 mg daily for 5 days, then 1 50 mg once a day every other day for 10-15 days. The course - 10-15 injections. Children aged 12-18 years - treated in the same manner as in / m injections of 100 mg.

Rectal Suppositories free from contouring package and then introduced into the rectum. The pre-empty the bowel.

Dose and duration of administration of the drug depend on the severity and duration of the disease.

For non-specific prevention and treatment of influenza and acute respiratory infections: 1 supp. 1 per day. Course - 5 supp. 100 mg.

In acute intestinal infectious diseases, accompanied by diarrhea syndrome: an initial dose - 2 supp. once, then 1 supp. 2 times a day until relief of symptoms of intoxication. Perhaps the subsequent continuation of the course 1 supp. with an interval of 72 hours course -. 20-25 supp. 100 mg.

In gastric ulcer and duodenal ulcer in the acute period: 2 days to 2 supp. 1 times a day, then 1 supp. with an interval of 72 hours course -. 15-25 supp. In chronic period: 5 days 1 supp. 1 times a day, then 1 supp. 72 hours course -. 20 supp. 100 mg.

In viral hepatitis the initial dose - 2 supp. once, then 1 supp. 2 times a day until relief of symptoms of intoxication and inflammation. The subsequent continuation of the course - 1 supp. with an interval of 72 hours course -. 20-25 supp. 100 mg.

In chronic recurrent diseases caused by herpes virus - 1 supp. daily - supp 5, then 1 supp.. a day - 20 supp. 100 mg.

In diseases caused by papilloma virus, - 5 days 1 supp. 1 times a day, then 1 supp. in one day. Course - 20 supp. 100 mg.

When urogenital diseases (chlamydial urethritis and trichomonas etiology, chlamydial prostatitis): 1 day 1 supp. twice, then 1 supp. - in one day. Course - 10-15 supp. 100 mg (depending on the severity of a pathological process).

When oophoritis, endometritis: in the acute period - 2 days 1 supp. 1 times a day, then 1 supp. with an interval of 72 hours In chronic course -. 5 days 1 supp. 1 times a day, then 1 supp. after every 72 hours of course -. 20 supp. 100 mg.

In acute and chronic septic diseases of the pelvic organs: in the acute period - 1 day 2 supp. once, 3 days 1 supp. daily, then 1 supp. a day - 5 supp. Course - 10 supp. In chronic period - 5 days 1 supp. 1 times a day, then 1 supp. after every 72 hours of course -. 20 supp. 100 mg.

For post-operative rehabilitation of patients with uterine fibroids and postoperative complications in women of reproductive age: 5 days 1 supp. 1 times a day, then 1 supp. in one day. Course - 20 supp. 100 mg.

For the prevention and treatment of surgical complications in the pre- and postoperative period (including cancer patients) administered 1 supp. 1 per day - 5 supp. before surgery, 5 supp. - 1 supp. after surgery in a day and 5 supp. - 1 supp. with an interval of 72 hours In severe disease the initial dose -. 2 supp. once or two times a day for 1 supp. Course - 20 supp. 100 mg.

In chronic recurrent furunculosis, erysipelas - 5 days 1 supp. 1 times a day, then 1 supp. in one day. Course - 20 supp. 100 mg.

When asthenic conditions, neurotic and somatoform disorders, with mental, behavioral and postabstinent disorders in patients with alcohol and drug dependence: 5 days 1 supp. daily, then 1 supp. 72 hours course -. 15-20 supp. 100 mg.

To improve physical performance: 1 supp. a day - supp 5, then 1 supp.. after 72 hours, the rate - 20 supp. 100 mg.

In inflammatory diseases of the mucous membranes of the mouth and throat, periodontal diseases: the initial dose - 1 supp. daily - supp 5, then 1 supp.. with an interval of 72 hours course -. 20 supp. 100 mg.

Rectally in children 6-11 years old, a dosage of 50 mg

For the prevention of influenza and acute respiratory infections, 50 mg (1 supp.) 1 times a day. Course - 5 supp.

In acute intestinal infectious diseases, accompanied by diarrhea syndrome: an initial dose - 2 supp. 50 mg once daily, followed by 1 supp. 2 times a day until relief of symptoms of intoxication. Perhaps the subsequent continuation of the course 1 supp. with an interval of 72 hours course -. 20 supp. 50 mg.

In gastric ulcer and duodenal ulcer: in the acute period - 2 days 2 supp. 1 times a day, then 1 supp. with an interval of 72 hours course -. 15-25 supp. In chronic period - 5 days 1 supp. 1 times a day, then 1 supp. 72 hours course -. 20 supp. 50 mg.

When viral hepatitis: the initial dose - 2 supp. once, then 1 supp. 2 times a day until relief of symptoms of intoxication and inflammation. The subsequent continuation of the course - 1 supp. with an interval of 72 hours course -. 20 supp. 50 mg.

In chronic recurrent diseases caused by herpes virus - 1 supp. daily for 5 days, followed by 1 supp. a day - 15 supp. Course - 20 supp. 50 mg.

In diseases caused by papilloma virus: 5 days 1 supp. 1 times a day, then 1 supp. in one day. Course - 20 supp. 50 mg.

When purulent surgical diseases (burn lesions, recurrent furunculosis, chronic osteomyelitis, gangrenous appendicitis with omentitom, purulent pleurisy): 1 supp. every day - 5 days, followed by 1 supp. every other day for 10 days. Course - 15 supp. 50 mg.

When asthenic conditions, neurotic and somatoform disorders: 5 days 1 supp. daily, then 1 supp. 72 hours course -. 15 supp. 50 mg. To improve physical performance: 1 supp. through the course of the day - 5 supp. 50 mg.

For the prevention and treatment of surgical complications in the pre- and postoperative period (including cancer patients): 1 supp. 1 per day - 5 supp. preoperatively, 5 - after surgery 1 supp. a day and 5 supp. c every 72 hours In severe disease the initial dose -. 2 supp. once or two times a day for 1 supp. Course - 20 supp. 50 mg.

In the treatment and prevention of urogenital infections of bacterial and viral etiology: 1 day 1 supp. 2 times a day, followed by 1 supp. in one day. Course - 10-15 supp. 50 mg (depending on the severity of a pathological process).

In inflammatory diseases of the mucous membranes of the mouth and throat, periodontal diseases: the initial dose - 1 supp. daily - supp 5, then 1 supp.. with an interval of 72 hours course -. 15 supp. 50 mg.

With frequent recurrent respiratory diseases and upper respiratory tract bacterial and viral aetiology (frequent acute respiratory viral infections, bronchitis, pneumonia, chronic tonsillitis, chronic otitis media, chronic adenoids): 1 supp. daily for 5 days, followed by 1 supp. every other day for 10 days. Course - 15 supp. 50 mg.

Hyoid: 1 table. daily to 4 times a day or 2 tablets. daily up to 2 times a day, depending on the diagnosis and the severity of the disease.

With frequent recurrent respiratory diseases and upper respiratory tract bacterial and viral aetiology (frequent acute respiratory viral infections, bronchitis, pneumonia, chronic tonsillitis, chronic otitis media, chronic adenoids): Apply 4 times a day on 1 tab. for 5 days, then Table 1. 4 times a day rate of up to 15 days.

For the prevention of acute respiratory infections and influenza: 1 table. 2 times a day, a course of 5-10 days.

In acute intestinal infectious diseases, accompanied by diarrhea syndrome: an initial dose - 2 tab. once, then 1 table. 3-4 times a day until relief of symptoms of intoxication within 3-5 days.

In gastric ulcer and duodenal ulcer: in the acute period - first 2 days - 1 table. 4 times a day, then every 3 days by Table 1. 4 times a day, the course - 2-3 weeks. In chronic period - 5 days on 1 tab. 4 times a day, then every 3 days by Table 1. 4 times a day rate of up to 3 weeks.

When viral hepatitis of various etiologies: in the acute period of disease the initial dose - 2 tablets. 2 times a day until relief of symptoms of intoxication and inflammation. Perhaps the subsequent continuation of the course in Table 1. 4 times a day, every 3 days before the course of 2-3 weeks.

In chronic recurrent diseases caused by herpes virus - 1 table. 4 times a day for 10 days. Then 1 table. 4 times a day, daily for 10 days.

In diseases caused by the human papilloma virus: 5 days and 1 table. 4 times a day, then one table. 4 times a day every other day course to 2-3 weeks.

When urogenital diseases (chlamydial urethritis and trichomonas etiology, chlamydial prostatitis). On the first day - 2 times 2 tablets, then 1 table. 4 times a day every other day course up to 2 weeks (depending on the severity of the pathological process).

When oophoritis, endometritis: in the acute period - 2 days 2 table. 2 times a day, then one table. Four times a day every 3 days for 3 weeks. In chronic period - 5 days on 1 tab. 4 times a day, then one table. 4 times a day, every 3 days before the course of 2-3 weeks.

In acute and chronic septic diseases of the pelvic organs: in the acute period of the first day - 2 tablets. 2 times a day, 3 days and then 1 tab. 4 times a day, then one table. 4 times a day every other day for 10 days. In chronic period - 5 days on 1 tab. 4 times a day, then Table 3-4. every 3 day course up to 3 weeks.

For post-operative rehabilitation of patients with uterine fibroids and postoperative complications in women of reproductive age: 5 days and 1 table. 4 times a day, then one table. 4 times a day every other day course up to 2 weeks.

When purulent surgical diseases (burn injury, chronic osteomyelitis, gangrenous appendicitis with omentitom, peritonitis, purulent pleurisy): Apply 4 times a day on 1 tab. for 5 days, then Table 1. 4 times a day rate of up to 15 days.

For the prevention and treatment of surgical complications in the pre- and postoperative period (including cancer patients): 1 table. 4 times a day for 5 days prior to surgery within 10 days after operation in Table 1. 4 times a day and during 3 weeks, 1 tab. 4 times in 3 days. In severe disease in the first day of the 2 table. Two times a day.

In chronic recurrent furunculosis, erysipelas: 5 days and 1 table. 4 times a day, then one table. 4 times a day rate of up to 3 weeks.

When asthenic conditions, neurotic and somatoform disorders, with mental, behavioral and postabstinent disorders in patients with alcohol and drug dependence: 5 days and 1 table. 4 times a day, then one table. 4 fold every 3 days for 3 weeks. To improve physical performance: 1 table. 4 times a day for 10 days, then 1 table. 4 times a day in the course of 3 days to 3 weeks.

In inflammatory diseases of the mucous membranes of the mouth and throat, periodontal diseases: the initial dose - 1 tab. 4 times a day for 5 days, then Table 1. 4 times a day in the course of 3 days to 3 weeks.

Galavit