Expiration date: 04/2025

Composition and form of issue:

Tablets

Active substance:

Paracetamol 250, 00 mg, propyphenazone 210, 00 mg and caffeine 50, 00 mg,

Auxiliary substance:

Magnesium stearate 13, 50 mg, sodium lauryl sulfate, sodium starch glycolate, silicon colloidal dioxide, calcium hydrophosphate dihydrate, cellulose microcrystalline, sodium crossarmellosis, glyceryl, dibegenate

Pharmacological action:

Caffetin® light is a combined drug analgesic action. Paracetamol and propyphenazone has analgesic and antipyretic action. The mechanism of action is associated with inhibition of prostaglandin synthesis. The presence of caffeine in the combined analgesics increases the absorption of components. The combination of the drug provides for a satisfactory analgesic effect, and the use of small amounts that are part of the components reduces the risk of side effects.

Pharmacokinetics:

Pharmacokinetic characteristics of the combined drugs are not significant, since the drugs are not intended for the treatment of chronic diseases and therefore are used as needed or in the form of short-term courses. All active components of the drug Caffetin® light have a similar pharmacokinetic profile, which justifies the rationality of analgesic combination. Absorbed very quickly and their maximum concentrations in plasma are achieved after 30 to 60 minutes after administration. Metabolized in the liver and excreted in the urine. During the biotransformation of paracetamol, a small amount of toxic metabolite N-acetil-p-benzo-quinoneimine is created, which can show disturbances in the liver

Indications:

Pain syndrome of moderate severity of different Genesis: headache and toothache, migraine, neuralgia, myalgia, post-traumatic pain, arthralgia, algodismenorrhea and fever in influenza infections.

Contraindications:

Increased individual sensitivity to the components of the drug, hepatic and / or renal failure, glucose deficiency-6-phosphate dehydrogenase, leukopenia, hematopoietic disorders, increased excitability, insomnia, angina on the background of coronary heart disease, pregnancy and lactation, children (up to 7 years)

Side effect:

Leukopenia, agranulocytosis, nausea, gastralgia, vomiting, increased activity of "hepatic" transaminases, increased excitability (especially in children), allergic reactions (skin rash, angioedema, itching, urticaria).

Interaction:

It is necessary to avoid the combination of the drug with barbiturates, antiepileptic agents, zidovudine, rifampicin and alcohol-containing drinks (the risk of hepatotoxic effect increases)

Dosage and administration:

Inside, adults-1 tablet 3-4 times a day. In case of severe pain, it is recommended to take 2 tablets at once. The maximum daily dose - 6 tablets. Children over 7 years appoint 1/4-1/2 tablets, 1-4 times a day. The duration of the drug is not more than 5 days. Increasing the daily dose of the drug or the duration of treatment is possible only after consultation with the doctor.

Overdose:

Symptoms: nausea, vomiting, ringing in the ears, stomach pain, sweating, pale skin, toxicomania. If you suspect poisoning, you must immediately seek medical help.

Precautionary measures:

With caution elderly, children's age, glaucoma.