Expiration date: 07/2025

The composition and form of issue:

Suppositories for rectal use 1 supp.

cocarboxylase hydrochloride 0, 025 g

Riboflavin 0, 002 g

lipoic acid 0, 012 g

excipients: cocoa butter or solid fat - up to a mass of 0.95 g

in contour cell packages of 5 PCs. in a pack of cardboard 2 packages.

Description of pharmacological action:

A combined drug whose effect is determined by the effects of its constituent vitamins and coenzymes.

Cocarboxylase hydrochloride has a metabolic effect, activates tissue metabolism. In the body, it catalyzes the carboxylation and decarboxylation of alpha-keto acids, participates in the processes of carbohydrate metabolism through participation in the pentose cycle indirectly promotes the synthesis of nucleic acids, proteins, and lipids. The drug is used to correct metabolic acidosis, cellular hypoxia and other metabolic disorders, chronic intoxication, helps normalize the function of the liver, kidneys, and cardiovascular system.

Riboflavin (vitamin B2) as a coenzyme of flavinproteins is involved in the regulation of redox processes, as well as carbohydrate, protein and fat metabolism, plays an important role in the synthesis of hemoglobin and maintaining normal visual function of the eye and the condition of the mucous membranes and skin.

Lipoic acid is involved in the oxidative decarboxylation of pyruvic acid and alpha-keto acids, in the regulation of lipid and carbohydrate metabolism, and plays an important role in the formation of energy in the body. Lipoic acid has a hepatoprotective effect, improves the detoxification function of the liver, and protects against the effects of Exo-and endotoxins.

Have corelib improves tissue metabolism under different physiological and pathological conditions in need of correction cofactors and substrates.

Dosage form:

Rectal suppositories

Pharmacological action:

A combined drug whose effect is determined by the effects of its constituent vitamins and coenzymes. Cocarboxylase hydrochloride has a metabolic effect, activates tissue metabolism. In the body, it catalyzes the carboxylation and decarboxylation of alpha-keto acids, participates in the processes of carbohydrate metabolism, and indirectly promotes the synthesis of nucleic acids, proteins, and lipids through participation in the pentose cycle. The drug is used to correct metabolic acidosis, cellular hypoxia, etc. metabolic disorders, chronic intoxication, helps to normalize the function of the liver, kidneys, and CCC. Riboflavin (vitamin B2) as a coenzyme of flavinproteins is involved in the regulation of redox processes, as well as carbohydrate, protein and fat metabolism, plays an important role in the synthesis of Hb and in maintaining normal visual function of the eye, the condition of the mucous membranes and skin. Lipoic acid is involved in the oxidative decarboxylation of pyruvic acid and alpha-keto acids, in the regulation of lipid and carbohydrate metabolism, and plays an important role in the formation of energy in the body. Lipoic acid has a hepatoprotective effect, improves the detoxification function of the liver, and protects against the effects of Exo-and endotoxins. Have corelib improves tissue metabolism under different physiological and pathological conditions in need of correction cofactors and substrates.

Indications:

Chronic tissue hypoxia, decreased immunity (bacterial and viral infections), chronic somatic diseases, chronic intoxication, a condition after suffering severe diseases, nutritional disorders (hypotrophy). Periods of intensive growth and formation of new functions in the child, intense physical and mental stress, stress. The period of the epidemic of infectious diseases (prevention).

Contraindications:

Hypersensitivity, proctitis, anorectal bleeding.

Side effect:

Rarely-allergic reactions: urticaria, itching, bronchospasm dyspepsia.

Dosage and administration:

Rectal, after a preliminary emptying of the bowels. Children from 1 year to 6 years - 1 suppository per day, from 6 to 14 years-1-2 suppositories per day. The duration of treatment is 10 days. Only 3-4 courses with intervals of 20 days (3-4 months).

Special instruction:

Criteria that determine the duration of therapy, along with the clinical state, are cytochemical indicators of activity of peripheral blood leukocyte enzymes (succinate dehydrogenase and glycerophosphate dehydrogenase).

Interaction:

No negative interaction was observed. The drug can be used in complex therapy.

The description of the drug Corilip is not intended for prescribing treatment without the participation of a doctor.

Indications:

As monotherapy or in the complex treatment of various pathological conditions in children, including:

• chronic tissue hypoxia
• reduced immunity (bacterial and viral infections)
• chronic somatic diseases, chronic intoxication, condition after severe diseases, nutritional disorders (hypotrophy)
• the period of intensive growth and formation of new functions in the child
• intense physical and mental stress
• as a General tonic for preventive purposes during the epidemic of infectious diseases.

Contraindications:

• hypersensitivity
• proctitis
• anorectal bleeding.

Side effect:

Rarely-allergic reactions: urticaria, itching, bronchospasm dyspepsia.

Drug interaction:

No negative interaction was observed. The drug can be used in complex therapy.

Dosage and administration:

Rectal, after a preliminary emptying of the bowels. Children from 1 year to 6 years — 1 sup./day, from 6 to 14 years-1-2 SUPPs./day. The duration of treatment is 10 days. In total-3-4 courses with intervals of 20 days (3-4 months).

Precautionary measures:

The criteria that determine the duration of therapy, along with the clinical state, are indicators of activity of peripheral blood leukocyte enzymes (succinate dehydrogenase and glycerophosphate dehydrogenase).