Expiration date: 05/2025

The composition and form of issue: 

1 tablet preparation schipuchego drink contains calcium lactate/gluconate 2, 94 g of calcium carbonate of 0, 3 g (equivalent to 500 mg or 12, 5 mmol of ionized calcium), as well as sodium bicarbonate, citric acid, sucrose, sodium saccharin in tubes of 10 and 20 PCs., in box 1 tuba.

In 1 effervescent tablet of 1000 mg contains: 

Active substances: calcium lactogluconate 2263, 00 mg of calcium carbonate 1750, 00my, equivalent to 1000mg or 25 mmol of ionized calcium.

Auxiliary substances: citric acid macrogol-6000, orange flavor (orange flavour contains sulphur dioxide (E220), butylhydroxyanisole (E320), sorbitol), aspartame, sodium bicarbonate.

Feature:

Effervescent tablets with high dose of lyophilized ionized calcium salts.

Pharmacological action:

Normalizes electrolyte balance, ensure adequate functioning of regulatory mechanisms.

Pharmacokinetics:

From the gastrointestinal tract absorbed about 30% of ionized calcium. Some types of food (e.g., spinach, rhubarb, bran, and grains) can decrease absorption. The plasma protein binding is 45%. Distributed to all tissues, the main part is deposited in the bones. Excreted in feces (about 80%) and urine (about 20%).

Indications:

Osteoporosis of different Genesis, prevention pre - and postmenopausal bone demineralization, rickets and osteomalacia (as a Supplement to the basic treatment), latent tetany condition, accompanied by an increased need for calcium (pregnancy and lactation, a period of intense growth in children) allergic conditions (supportive treatment).

Contraindications:

Hypersensitivity, hypercalcemia, severe hypercalciuria, severe renal insufficiency.

Side effects:

Rarely — flatulence, constipation or diarrhea.

Drug interactions:

Estramustine reduces the absorption of etidronate and other bisphosphonates, phenytoin, quinolone, tetracycline, fluoride preparations. Vitamin D and its derivatives increase the absorption of calcium (avoid concomitant use), thiazide diuretics reduce the excretion and therefore increase the likelihood of hypercalcaemia. High doses of calcium can reduce the effectiveness of verapamil and other CCB, increase the risk of arrhythmias in patients taking digitalis preparations. Citric acid, part of the Calcium-Sandoz Forte, enhances the absorption of aluminum.

Method of application and dose:

Inside, 500-1000 mg/day, previously dissolved in 1 Cup water. In severe cases and in the first week of treatment the dose can be increased up to 2000 mg/day.

Precautions:

In patients with hypercalciuria, impaired renal function or when you specify to urolithiasis in anamnesis it is recommended that regular monitoring of the level of excretion of calcium with urine.

Diabetics be aware that carbohydrates make 1 table. is 870 mg.

Patients on nizkosoleva diet, you must keep in mind that 1 table. contains 270 mg of sodium.