Expiration date: 01/2025

DESCRIPTION

Gentaprim is a complex antibacterial drug in the form of an injectable solution for the treatment of cattle with infectious diseases of the respiratory and gastrointestinal tracts and the genitourinary system, as well as mixed infections caused by microorganisms sensitive to the combination of sulfadimethoxine-trimethoprim and gentamicin. It is produced in the form of a clear solution for injection.

STRUCTURE

It contains 30 mg of gentamicin sulfate (corresponding to 20 mg of the base), 200 mg of sulfadimethoxine and 40 mg of trimethoprim in 1 ml as active ingredients.

PHARMACOLOGICAL PROPERTIES

Gentamicin has a broad spectrum of antimicrobial action, is active against most Gram-negative and Gram-positive microorganisms, including proteus, Escherichia, salmonella and staphylococci. Sulfadimethoxine and trimethoprim, which are part of the drug, show a synergistic effect, have a pronounced antibacterial effect on a wide range of Gram-positive and gram-negative microorganisms that cause infectious diseases of animals. Sulfadimethoxine and trimethoprim separately have a bacteriostatic effect, and together they give the drug a bactericidal effect. Cases of resistance of pathogenic microbes to gentaprim are extremely rare.

INDICATIONS

It is prescribed to cattle, horses, small cattle, pigs, dogs and cats for the treatment of infections caused by bacteria sensitive to gentamicin and the combination of sulfadimethoxine-trimethoprim, including: respiratory tract infections (pneumonia, bronchopneumonia, bronchitis), diarrhea, dysentery, colibacteriosis, enteritis, septicemia, metritis and endometritis, pyelitis, pyelonephritis, cystitis, urethritis, pasteurellosis, mastitis, mumps, skin infections, actinomycosis, purulent abscesses, complications of viral diseases, salmonellosis, parainfluenza.

DOSAGE AND APPLICATION

Gentaprim is administered to animals intramuscularly at a dose of 1 ml per 10 kg of animal weight every 12 to 24 hours for 3 to 5 days. As prescribed by a veterinarian, the drug can be used for 7 days or more. In case of renal insufficiency, it is recommended to reduce the dose of gentaprim, depending on the activity of the kidneys.

SIDE EFFECTS

With proper use and dosage, side effects are usually not observed. In some cases, allergic reactions are noted in the form of erythema and itching at the point of administration of gentaprim. Intoxication due to an overdose of the drug is almost impossible. If intoxication has occurred, symptomatic treatment is used.

CONTRAINDICATIONS

Increased individual sensitivity to the components of the drug. Simultaneous or sequential use of gentaprim with other ototoxic and nephrotoxic drugs (streptomycin, kanamycin, neomycin), as well as with diuretics and muscle relaxants is not allowed. Do not administer in conjunction with drugs containing paraaminobenzoic acid (PABA), which counteracts sulfonamides. With great caution, gentaprim should be prescribed to animals with impaired renal function.

SPECIAL INSTRUCTIONS

Slaughter of animals for meat is allowed 30 days after stopping the administration of the drug. The meat of animals forcibly killed before the expiration of the specified period can be used for feeding fur-bearing animals or for the production of meat and bone meal. Milk obtained from animals during the use of gentaprim and before the expiration of 4 days after the last administration of the drug, it is forbidden to use for food purposes. Such milk after heat treatment is used for feeding animals.

SHELF LIFE AND STORAGE

In a dry, cool, protected from light and out of the reach of children and animals at a temperature of 5 to 25 °C. Shelf life — 3 years.