Expiration date: 01/2025
DESCRIPTION
Diastop is an antibacterial drug for the treatment of gastrointestinal diseases of bacterial etiology in piglets and calves. Preparation form: powder for oral administration, is a multicomponent mixture.
The contents of the package No. 1 is a homogeneous powder of light yellow with a greenish tinge of color, soluble in warm water.
The contents of the package No. 2 is a hygroscopic powder of white or slightly yellowish color, soluble in warm water.
STRUCTURE
Package No. 1 contains: dioxidine – 1.0 g, norfloxacin hydrochloride – 1.0 g, sodium chloride – 5.0 g, potassium chloride – 0.2 g, glucose – 18.0 g.
Package No. 2 contains: low-molecular-weight polyvinylpyrrolidone-24.8 g.
PHARMACOLOGICAL PROPERTIES
Norfloxacin is effective against Gram-positive and Gram-negative microorganisms: Escherichia, pasteurella, Salmonella, staphylococci, mycoplasma.
Dioxidine is effective against gram-negative, gram-positive pathogenic and conditionally pathogenic aerobic and anaerobic microorganisms of spore-forming and non-spore-forming species.
The drug is active against microorganisms with low sensitivity and resistance to antibiotics and other chemotherapeutic agents. Sodium and potassium chlorides normalize the water-salt balance. Glucose is a source of energy material that is easily absorbed by the body, which increases the body's resistance and improves its functions. Polyvilpyrrolidone helps to remove toxins from the gastrointestinal tract and the body as a whole.
The maximum concentration of active substances of Diastop-AF in the blood is reached after 1-3 hours and is maintained at the therapeutic level for 24 hours. They are excreted from the body mainly in the urine.
According to the degree of exposure to the body, Diastop according to GOST 12.1.007 belongs to low-hazard substances (hazard class 4).
Diastop is incompatible with antibiotics from the groups of chloramphenicol, macrolides and tetracyclines.
INDICATIONS
The drug is prescribed to calves and piglets for the treatment of gastrointestinal diseases of bacterial etiology.
APPLICATION
Before use, the contents of packages No. 1 and No. 2 are dissolved in 1 liter of warm (37°C - 38°C) drinking water. The therapeutic solution is prepared immediately before use and immediately used. The Diastop solution is used individually orally at a dose of 10 ml/kg of body weight daily 2 times a day with an interval of 12 hours for 3 days. With a severe course of the disease on the first day, the drug is drunk in a double dose.
SIDE EFFECTS
With proper use and dosage, side effects and complications are usually not observed. In case of allergic reactions, the use of the drug is discontinued and desensitizing therapy is performed.
Slaughter of animals for meat is allowed no earlier than 5 days after the last introduction of the Diastope. The meat of animals forcibly killed before the expiration of the specified period can be used for feeding carnivorous animals or for the production of meat and bone meal.
CONTRAINDICATIONS
Increased individual sensitivity of the animal to the components of the drug, including in the anamnesis. It is forbidden to use Diastop-AF simultaneously with bacteriostatic antibiotics (levomycetin, macrolides and tetracyclines) and nitrofurans, due to a possible decrease in antibacterial activity, as well as with theophiline and non-steroidal anti-inflammatory drugs.
SAFETY PRECAUTIONS
When working with a Diastop, you should follow the general rules of personal hygiene and safety, provided for when working with medicines.
STORAGE
The diastop is stored with caution in a dry place, protected from direct sunlight and out of the reach of children and animals. Separately from food and feed at a temperature of 5°C to 20°C. The shelf life of the drug, subject to storage conditions, is 2 years from the date of manufacture. It is forbidden to use the drug after the expiration date.
