Expiration date: 01/2025
DESCRIPTION
Amoxivet LA (Amoxivet LA) – veterinary drug is used for large and small cattle, pigs with bacterial infections. In appearance, the drug is a suspension from white to light yellow, resuspending when shaken.
STRUCTURE
In 1.0 ml of the drug contains 0.15 g of amoxicillin (in the form of amoxicillin trihydrate), excipients, filler up to 1.0 ml.
PHARMACOLOGICAL PROPERTIES
Amoxicillin, which is part of the drug, belongs to the semi-synthetic antibiotics of the penicillin series.
The mechanism of action of the drug is based on the violation of the synthesis of the bacterial cell wall by inhibiting the enzymes transpeptidase and carboxypeptidase, which leads to a violation of the osmotic balance and cell destruction.
The drug has a wide spectrum of bactericidal action against gram-positive and gram-negative microorganisms, such as Actynomyces spp., Bacillus antacis, Clost,,idium spp., sshupeitegiit spp., E1· - ysipeloth,,ix rhusiopathiae, Listegia monocytogenes, Staphylococcus spp., St1'eptococcus spp., Escherichia coli, Salmonella spp., Fusobacteidium spp., Haemophilus spp., Pasteiu"ella spp., p., oteus spp., Leptospira spp.and others. It has no effect on viruses, chlamydia, mycoplasma, rickettsia.
After parenteral administration of the drug, the maximum concentration of amoxicillin trihydrate in the blood serum is reached after 1-2 hours and is maintained at the therapeutic level for 48 hours. The antibiotic is excreted from the body with urine and feces, mainly in unchanged form.
DOSAGE AND APPLICATION
Amoxivet LA is used in large and small cattle, pigs for bacterial infections of the respiratory and genitourinary systems, skin and soft tissue diseases caused by microorganisms sensitive to amoxicillin.
The drug is used intramuscularly at a dose of 1.0 ml per 10.0 kg of animal weight once every two days at equal intervals until recovery, but no more than three injections.
The maximum volume of the drug for administration in one place should not exceed 20 ml for cattle, 10 ml for pigs, 5 ml for small cattle and calves, and 2 ml for piglets.
Before use, the bottle with the drug must be thoroughly shaken until a homogeneous suspension is obtained.
SPECIAL INSTRUCTIONS
If allergic and other adverse reactions occur, the drug is canceled and antihistamines and calcium preparations (calcium chloride, calcium gluconate, calcium borgluconate) are prescribed.
Slaughter of animals for meat is allowed no earlier than 28 days after the last administration of the drug. In the case of forced slaughter of animals before the deadline, the meat is used for feeding carnivores. Milk is allowed to be used for food purposes no earlier than 4 days after the last administration of the drug. Milk obtained earlier than the specified period can be used for feeding animals after heat treatment.
CONTRAINDICATIONS
The use of the drug is contraindicated for small herbivores and rodents (rabbits, guinea pigs, hamsters). Do not use the drug together with tetracyclines, amphenicolamines, sulfonamides.
SIDE EFFECTS
When using the drug in the recommended doses in accordance with the instructions, side effects and complications are not observed, but in animals with increased sensitivity to lactam antibiotics (penicillins, cephalosporins), various allergic reactions are possible.
SHELF LIFE AND STORAGE
The drug is stored according to list B in a dry, protected from light place at a temperature of plus 5 °C to plus 25 °C. The shelf life of the drug is 2 years from the date of manufacture, subject to the rules of storage and transportation.
