Expiration date: 02/2026
The composition and form of issue:
Sangviritrin pills
Tablets, soluble in the intestine.1 tablet contains:
sangviritrin (in terms of 100% substance) 0.005 g
sugar (sucrose) 0.093 g
excipients: cellulose M?8 water-soluble, magnesium stearate up to receive the tablets of 0.1 g (without shell)
shell:
Opadry II white OY-LS?28911 acrylis 93O8359 white Opadry II red 85F25163 — to make a pill mass of 0.11 g
banks in dark glasses to 30 or 50 PCs. or contour acheikova packing 10 PCs in the paper cartons 1 Bank, 3 or 5 packs.
Sangviritrin Liniment 0,5%. 100 g contains:
sangviritrin (in terms of 100% substance) 0.5 g
excipients: emulsifier No. 1 tween-80 castor oil, sorbic acid ethyl alcohol 95% purified water
the aluminium tubes of 10 or 20 g or in the banks dark glasses to 10 or 20 grams in a cardboard bundle 1 tuba or Bank.
Sangviritrin solution of 0.2%
Solution alcoholic for external use. 100 ml contains:
sangviritrin (in terms of 100% substance), 0.2 g
in dark glass bottles of 50 ml in a cardboard pack 1 bottle.
Sangviritrin liniment 1%
Liniment 100g contains:
sangviritrin (in terms of 100% substance) 1 g
excipients: emulsifier ?1 twin?80 castor oil, sorbic acid ethyl alcohol 95% purified water
the aluminium tubes to 20 grams in a cardboard bundle 1 tuba.
Description pharmaceutical form:
Tablets: biconvex shape and a dark orange to brownish orange, film-coated.
Liniment: homogeneous dense mass from light orange to orange in color with a specific smell.
Feature:
Antimicrobial agent of plant origin. Is the sum of bisulfate natural alkaloids sangvinarina and heleritrina (similar in structure and properties of Quaternary bezoperatsionnye alkaloids), derived from herbs of Maclay cordate (Macleaya cordata Willd.) R. Br. and Maklai small (Macleaya microcarpa Maxim.) Fedde.
Pharmacological action:
It has a broad spectrum of antimicrobial activity, acting against gram-positive and gram-negative bacteria (of the genus Staphylococcus, Streptococcus, Enterococcus, Shigella, Escherichia, Salmonella, Proteus, Acinetobacter, Citrobacter, Pseudomonas, Serratia, Klebsiella, Antracoides, Cryptococcus), pathogenic fungi of the genus Microsporum, Trichophyton, Nocardia, Aspergillus, yeast-like fungi of the genus Candida, including multidrug resistant strains of microorganisms, as well as Actinomyces and some pathogenic protozoa (Entamoeba histolytica, Trichomonas vaginalis). At therapeutic doses it acts bacteriostatic. The mechanism of antimicrobial action Sangviritrin includes the suppression of bacterial nucleases, the violation of the processes of the permeability of the cell walls and partitions division. The drug also has weak anticholinesterase activity and may be effective for myopathy and disorders caused by cerebral palsy and polio.
Indications:
Pills. Complex therapy of acute and chronic infectious and inflammatory diseases: acute intestinal infections (dysentery, salmonellosis, foodborne diseases), wound infections and various infectious complications caused by pathogens (bacteria carrying reconvalescence), diseases associated with disruption of normal microflora (dysbiosis), as well as diseases caused by pathogenic fungi (faringomikoza, candidiasis, microsporia).
The water-alcohol solution. External and chronic suppurative otitis media, pyoderma, superficial blastomycosis, onychomycosis, dermatomycosis, including complicated mixed flora prevention of inflammatory complications and wound infection in surgical interventions.
Liniment. Infectious-inflammatory diseases of the skin and mucous membranes of bacterial and fungal etiology, including Candida albicans, in dentistry — periodontitis, aphthous stomatitis, ulcerative-necrotic gingivostomatitis in the surgery with infected burns, nonhealing wounds and ulcers, in gynecology, in endocervicitis, colpitis, vaginitis, erosion of cervix in dermatology — with pyoderma, superficial blastomycosis, ringworm.
Contraindications:
Hypersensitivity to the drug, liver and kidney dysfunction, epilepsy.
For tablets more: hyperkinesis, bronchial asthma, coronary heart disease.
Dosage forms for external application optional: fungal skin infections with symptoms brought about by eczematization of.
Side effects:
Allergic reactions.
Pills in addition: nausea, vomiting, abdominal pain. These effects disappear with the end of the reception.
Dosage forms for external application optional: burning sensation.
Drug interactions:
Not described.
Method of application and dose:
Sangviritrin pills
Inside, after eating, without chewing. Adults usually 2 table. 3-4 times a day (if necessary up to 9 tables./day). Children 11-15 years in the 1-2 table. 3 times a day (daily dose up to 6 table). 4-10 years — 1 table. 3-4 times a day, 1-3 years — 1 table. on life year (1 year — 1 tab./days 2 years — 1 table. 1-2 times a day 3 years — 1 table. 2-3 times a day, etc.). The duration of treatment is: acute intestinal infections (dysentery, salmonellosis, foodborne diseases), 5-7 days (if needed 10 days) dysbiosis — up to 10-14 days, the bacteria carrying (bacterial excretion) — 7-14 days faringomikoza, candidiasis — up to 14 days microsporia — 4-5 weeks. After consultation with the doctor, repeated treatment is possible.
Sangviritrin solution of 0.2%
Topically, 0.2% aqueous-alcoholic solution daily treated skin folds of newborns (2 times a day for the first 5-6 days of life) using a sterile cotton swab.
Endocervicitis, colpitis, vaginitis, cervical erosion: irrigation, irrigation and lotions 0.005–0.01% warm aqueous solutions (prepared ex tempore of 0.2% aqueous-alcoholic solution by dilution of 40 times is 1 teaspoon per 200 ml water) every day 1-2 times a day. The course of treatment — 5-10 procedures.
Prevention of inflammatory complications: daily washing and a sterile bandage on the wound with 0,2% water-alcohol solution for 3-4 days. Then the wound was treated with 0.2% aqueous - alcoholic solution and place dry bandage. The rate is determined by the period of wound healing and lasts 7-10 days if uncomplicated.
Infected burn wounds, nonhealing wounds and ulcers, open fractures, etc.: washing and dressing with 0.01–0.1% aqueous solution every day 1-2 times a day (nonhealing wounds), or every other day (infected burns).
Tonsillitis: adults and children over 5 years — treatment of the tonsils 0.2% vodno-spirtovm solution 1 time per day during 2-5 days rinsing 0.005% aqueous solution daily 3-5 times a day. Children under 5 years of age — oxidative 0.005% aqueous solution of the mucous membrane of the oral cavity 3-4 times per day. The course duration is 3-7 days.
Periodontitis: after removing dental sediments and curettage pathological gingival pockets in them for 20 min is administered turundy thin, wetted 0.2% vodno-spirtovm or 0.01–0.1% aqueous solution every day or two. The treatment course is 4-6 treatments.
The stomatitis of various etiology: the application of 0.2% aqueous-alcohol solution or 0.01–0.1% aqueous solutions 2-3 times a day during 2-5 days. Children over 5 years — rinsing 0.005–0.01% warm aqueous solutions, children younger than 5 years mucosa of the mouth lubricated with a 0.005% aqueous solution.
Otitis externa: turundy with 0.2% aqueous-alcoholic solution at 10-15 min is introduced into the ear canal 2-3 times a day. The minimum course of treatment — 2 weeks.
Chronic suppurative otitis media: adults: 5-8 drops 0.2% vodno-spirtovm solution children 1-2 drops 0.2% vodno-spirtovm solution in the ear canal 3-4 times a day.
Pyoderma, superficial blastomycosis, onychomycosis and ringworm: treatment of lesions of the 0.2% aqueous-alcoholic solution every day 1-2 times a day.
The maximum daily dose sangviritrin for adults and children over 5 years: water-alcohol solution — 15 ml aqueous solutions — 30 ml for children under 5 years of age: aqueous-alcoholic solution, 10 ml of aqueous solutions — 20 ml., If necessary, the drug can be used for several months.
Sangviritrin (liniment of 0.5%)
Sangviritrin liniment 1%
Locally
Diaper rash and abrasions in newborns: apply 1% liniment 1-2 times a day for 1-3 days.
Endocervicitis, colpitis, vaginitis, erosion of cervix: 0.5 or 1% liniment applied to the walls of the vagina and cervix every day or two. The course of treatment — 5-10 procedures.
Infected burn wounds, nonhealing wounds and ulcers, open fractures, etc.: bandages with 0.5–1% liniment daily 1-2 times a day (nonhealing wounds), or every other day (infected burns).
The stomatitis of various etiology: applications of 0.5–1% liniment 2-3 times a day during 2-5 days.
Pyoderma, superficial blastomycosis, onychomycosis and ringworm: treatment of lesions of 0.5 or 1% liniment daily 1 -2 times a day.
The maximum daily dose sangviritrin for adults and children over 5 years: liniment — 3 g for children up to 5 years, liniment — 2 G. If necessary, the drug can be used for several months.
Special instructions:
Pills. The composition of Opadry II white OY-LS?28911 consists of: hydroxypropyl methylcellulose, lactose monohydrate, Polydextrose, polyethylene glycol 4000. Part of Acrilic white 93 ?18359 — methacrylic acid copolymer, talc, titanium dioxide, triethylcitrate, silica colloidal anhydrous, sodium bicarbonate, sodium lauryl sulfate. The composition of Opadry II red 85F25163 — polyvinyl alcohol, talc, macrogol/peg 3000, titanium dioxide, iron oxide yellow, iron oxide red.
