Expiration date: 05/2025

Composition
1 capsule contains active substance: fluconazole 50 mg or 150 mg
Pharmacotherapeutic group
Antifungal agent
Code ATX
J02AC01
Pharmacological action
Antifungal. A representative of the class of triazole antifungal agents, is a powerful selective inhibitor of Sterol synthesis in the cell of fungi.
Indications for use
Cryptococcosis, including cryptococcal meningitis and other localizations of the infection. Generalized candidiasis, including Candida, disseminated Candida and other forms of invasive Candida infections. Mucosal candidiasis, genital candidiasis. Prevention of fungal infections in patients with malignant tumors. Fungal infections of the skin, deep endemic mycoses.
Contraindications
Simultaneous administration of terfenadine or astemizole and other drugs that extend THE Qt interval. Hypersensitivity to the drug or similar in structure to the azole compounds. Children under 3 years.
Dosage and administration
Inside.
Adults with cryptococcal meningitis and cryptococcal infections of other localizations are usually prescribed 400 mg (8 capsules of 50 mg) on the first day, and then continue treatment at a dose of 200 mg (4 capsules of 5 mg)- 400 mg (8 capsules of 50 mg) once a day.
When candidemia, disseminated candidiasis and other invasive candidal forage Doha infections is usually 400 mg the first day followed by 200 mg Duration of therapy depends on clinical effectiveness.
With vaginal candidiasis, fluconazole is taken at a dose of 150 mg once.
With skin mycosis, the recommended dose is 150 mg 1 time per week or 50 mg 1 time/day.
In deep endemic mycoses may require the use of the drug at a dose of 200-400 mg / day for up to 2 years.
In children, as in similar infections in adults, the duration of treatment depends on the clinical and mycological effect. In children, the drug should not be used in the daily dose, which would exceed that in adults. The drug is used daily 1 time a day.
Form release
50mg of 7 capsules per pack
150 mg 1, 2 or 4 capsules per pack