Expiration date: 04/2025

Structure and Composition:

1 capsule contains 10 mg periciazine tube 50 pcs., In box 1 tube or in blister 50 pcs., In the box, in a cardboard box 1 pencil case.

1 drop of 4% solution for oral administration - 1 mg vial of 125 ml, in a carton one bottle.

Pharmachologic effect:

Blocks dopaminergic receptors (mainly D2), adrenergic, serotonergic, m-cholinergic receptors.

Testimony:

Psychopathy (excitable and hysterical type), psychopathic disorders of organic origin with a predominance sthenic affect and behavior, psychopathic state in schizophrenia (including geboidnye), paranoid states in the framework of organic, vascular, presenile and senile diseases epilepsy with affective-explosive characterological symptoms and dysphoric states.

Contraindications:

Toxic agranulocytosis history, angle-closure glaucoma, porphyria, prostate adenoma.

Side effect:

Depression, dyskinesia: early (spasmodic torticollis, oculomotor crisis, trismus) and later, extrapyramidal disorders orthostatic hypotension, dry mouth, constipation, paresis of accommodation, urinary retention, impotence, frigidity, amenorrhea, galactorrhea, gynecomastia, hyperprolactinemia, increased body mass index, hyperthermia, cholestatic jaundice, photosensitivity, agranulocytosis (very rare).

Drug Interactions:

It enhances the effect of drugs, analgesics, barbiturates, alcohol, antihypertensives, tranquilizers.

Dosage and administration:

Inside, at the beginning of treatment - 5-10 mg (patients with hypersensitivity - 2-3 mg) 3-4 times a day, the average daily dose - 30-40 mg, the maximum - 50-60 mg.

Precautionary measures:

In the event of hyperthermia treatment should be discontinued immediately. Particularly careful monitoring is required in the treatment of epilepsy (in connection with a possible decrease in epileptic threshold), and parkinsonism. Carefully prescribed to elderly patients (sedative and hypotensive effects) in cardiovascular disease, renal or hepatic insufficiency transport drivers and those working with machinery (drowsiness and reduced, especially at the beginning of treatment, response).