Expiration date: 02/2025
Clinico-pharmacological group:
Preparation for rehydration and detoxification for parenteral use
Release form, composition and packaging
Solution for infusion 0.9%. 100ml contains:
sodium chloride 900 mg
100 ml - polyethylene bottles (10) - packs of cardboard.
500 ml - bottles plastic (10) - packs of cardboard.
1 l bottle, polyethylene (10) - packs of cardboard.
100 ml - polyethylene bottle.
1 l - plastic bottle.
250 ml - bottle plastic.
500 ml - bottles plastic.
100 ml - polyethylene bottles (20) - boxes: cardboard.
Description the active component of the drug "Sodium chloride"
Pharmacological action
Ions of sodium and chlorine are the major inorganic components of the extracellular fluid, maintaining the osmotic pressure of blood plasma and extracellular fluid. Isotonic solution fills a deficit of body fluids during dehydration. Hypertonic solution of sodium chloride at/in the introduction provides a correction of osmotic pressure of extracellular fluid and blood plasma. When applied topically in ophthalmology sodium chloride has anti-edema effect.
Testimony
Isotonic solution: the dehydration of various origins. To maintain the volume of blood plasma during and after surgery. As a solvent for various drugs.
Hypertonic solution: disorders of water and electrolyte metabolism: deficiency of sodium and chlorine ions, Hypo dehydration of various origins (due to prolonged vomiting, diarrhoea, burns, gastric fistula, pulmonary hemorrhage, intestinal bleeding).
Eye drops and ointment: irritation of the cornea with inflammatory and allergic diseases (in combination therapy).
The dosage regimen
Isotonic solution of sodium chloride is injected into/in, n/a, and enemas and is also used for washing wounds, eyes, mucous nasal cavity. Often administered in/in, depending on the clinical situation - up to 3 l/day.
Hypertonic sodium chloride solution injected I/V. the dose for the on/in the introduction of the jet can reach 10-30 ml. for conditions requiring immediate replenishment of sodium and chlorine ions, the drug is injected in/in the drip in a dose of 100 ml.
Locally and topically applied depending on the dosage forms and treatment regimens.
Side effects
Possible: nausea, vomiting, diarrhea, stomach cramps, thirst, lacrimation, sweating, fever, tachycardia, arterial hypertension, impaired renal function, edema, shortness of breath, headache, dizziness, anxiety, weakness, twitching and muscle hypertonicity.
When external and local application, adverse reactions to date are not installed.
Contraindications
Hypernatremia, state of hyperhydration, the threat of pulmonary edema, brain.
Application for violations of renal function
With careful use of large amounts of sodium chloride in patients with violation excretory function of the kidneys.
Special instructions
With careful use of large amounts of sodium chloride in patients with violation excretory function of the kidneys, with hypokalemia. The introduction of large amounts of the solution can result in chloride acidosis, hyperhydration, increase of potassium deduction from the organism.
Hypertonic saline is not used, p/and/m.
With prolonged use requires monitoring of electrolytes in the plasma and daily urine output.
The temperature of the intravenous solution should be 38°C.
