Expiration date: 07/2025

The composition and form of issue

Epagel gel for local and external use:

1 g of gel contains recombinant human interferon Alfa-2b 10 thousand IU, tubes of 2 g, 3 g, 5 g or 10 g.

Pharmacological action

Included in the gel composition of Interferon alpha-2 recombinant has a broad spectrum antiviral activity (influenza, herpes, etc.), bacteriostatic and anti-inflammatory, and antitumor and immunomodulatory activity.

Testimony

Acute hepatitis B, chronic hepatitis B, chronic hepatitis C.

Hairy cell leukemia, chronic myelogenous leukemia, renal cell carcinoma, Kaposi's sarcoma in the background of AIDS, cutaneous T-cell lymphoma (mycosis fungoides and the syndrome of Sezari), malignant melanoma.

Method of application and doses

In the treatment of herpetic lesions, the ointment is applied to affected areas of the skin and mucous membranes with a thin layer 2 times a day at intervals of 12 h and dried for 10-15 min to form a protective film. The duration of treatment is 3 to 5 days until complete disappearance of disturbances of the integrity of the skin and mucous membranes.

Side effects

The drug is not give side effects.

Contraindications

Severe cardiovascular disease, decompensated cirrhosis, severe depression, psychosis, alcohol or drug dependence, hypersensitivity to interferon Alfa-2b.

Application of pregnancy and breastfeeding

The use of Inpages when pregnancy is possible only in the case when the expected benefit of therapy for the mother outweighs the potential risk to the fetus.

Unknown, selects whether interferon Alfa-2b in breast milk. If necessary, use during lactation should decide the issue of termination of breastfeeding.

Women of childbearing age during treatment should use reliable contraception.

Special instructions

Be wary of Infiel in patients with impaired renal function, liver, bone marrow hematopoiesis and the propensity to suicidal attempts.

In patients with diseases of the cardiovascular system possible arrhythmias. If the arrhythmia does not decrease, or increases, the dose should be reduced in 2 times, or stop treatment.

During treatment requires monitoring of neurologic and mental status.

Storage conditions and shelf life

The drug should be stored in a dry, protected from light place at temperature not above 20°C. shelf Life - 2 years.

Infagel
(Interferon
Alfa-2a)