Formulations having the ability to shield the postsynaptic alpha-adrenoceptors by contact with neurotransmitter (noradrenaline) or agonists, circulating in the blood (endogenous adrenaline, drugs) divided by selective alpha1 blockers (alfuzosin, prazosin, doxazosin, tamsulosin, terazosin, and others). and nonselective blockers and alpha 1 and alpha2-adrenoceptors (phentolamine, tropodifen, ergot alkaloids and their derivatives, nicergoline, proroksan, butiroksan et al.). Drugs in this group hinder the passage of impulses through the vasoconstrictor adrenergic synapses and cause due to this expansion of arterioles and precapillaries. Another effect mediated blockade of alpha1-adrenergic receptors, is to improve the urodynamics in benign prostatic hyperplasia (see. MEANS, affects the metabolism in the prostate gland, and proofreaders urodynamics).