• Arbidol (Umifenovir) Maximum 200mg 10 capsules

Expiration date: 03/2022

Form release: Capsules

Composition, 1 capsule contains: umifenovir 200mg

Pharmacological action: an antiviral and immunostimulatory agent.

Pharmacodynamics:

Antiviral agent, has an immunomodulatory and anti-influenza effect, specifically suppresses viruses of influenza A and B, severe acute respiratory syndrome (SARS). Prevents contact and penetration of viruses into the cell, suppressing the fusion of the virus's lipid envelope with cell membranes. Has interferon-inducing action, stimulates humoral and cellular response of immunity, the phagocytic function of macrophages, increases the body's resistance to viral infections. Reduces the incidence of complications associated with viral infection, as well as exacerbations of chronic bacterial diseases.

Therapeutic effectiveness in viral infections is shown in reducing the severity of General intoxication and clinical phenomena, reducing the duration of the disease.

It belongs to low-toxic drugs (LD50 >, 4 g / kg). It does not have any negative effects on the human body when used orally in the recommended doses.

The pharmacokinetics

It is quickly absorbed and distributed to organs and tissues. The maximum concentration in blood plasma when taken at a dose of 50 mg is reached in 1, 2 hours, at a dose of 100 mg-in 1, 5 hours. it is Metabolized in the liver. The half-life is 17-21 hours. About 40% is excreted unchanged, mainly with bile (38.9%) and in a small amount by the kidneys (0.12%). During the first day, 90% of the administered dose is removed.

Indications for use

Prevention and treatment in adults and children: influenza a and B, SARS, severe acute respiratory syndrome (SARS) (including complicated by bronchitis, pneumonia), secondary immunodeficiency conditions, complex therapy of chronic bronchitis, pneumonia and recurrent herpes infection.

Prevention of postoperative infectious complications and normalization of the immune status.

Complex therapy of acute intestinal infections of rotavirus etiology in children older than 3 years.

Contraindications

Hypersensitivity to the drug, age up to 3 years.

Method of administration and dosage.

Inside, before eating.

Single dose: children from 3 to 6 years - 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg (2 capsules of 100 mg or 4 capsules of 50 mg).

For non-specific prevention:

In direct contact with patients with flu and other SARS:

children from 3 to 6 years - 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg once a day for 10-14 days.

During an epidemic of influenza and other acute respiratory infections, to prevent exacerbations of chronic bronchitis, relapse of herpetic infection:

children from 3 to 6 years - 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg twice a week for 3 weeks.

For the prevention of SARS (in contact with the patient):

adults and children over 12 years of age are prescribed 200 mg once a day. Children from 6 to 12 years of age 100 mg once a day (before meals) for 12-14 days.

Prevention of postoperative complications:

children from 3 to 6 years - 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg 2 days before surgery, then 2 and 5 days after surgery.

For Treatment:

Flu, other acute respiratory infections without complications:

children from 3 to 6 years - 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg 4 times a day (every 6 hours) for 5 days.

Flu, other acute respiratory infections with the development of complications (bronchitis, pneumonia, etc.):

children from 3 to 6 years - 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg 4 times a day (every 6 hours) for 5 days, then a single dose once a week for 4 weeks.

Severe acute respiratory syndrome (SARS):

children over 12 years of age and adults-200 mg 2 times a day for 8-10 days.

In the complex treatment of chronic bronchitis, herpetic infection:

children from 3 to 6 years - 50 mg, from 6 to 12 years-100 mg, older than 12 years and adults-200 mg 4 times a day (every 6 hours) for 5-7 days, then a single dose 2 times a week for 4 weeks.

Complex therapy of acute intestinal infections of rotavirus etiology in children older than 3 years:

from 3 to 6 years-50 mg, from 6 to 12 years-100 mg, over 12 years-200 mg 4 times a day (every 6 hours) for 5 days.

Side effect

Rarely-allergic reactions.

Special instructions

Influence on the ability to drive vehicles and other mechanisms that require increased concentration of attention

It does not show Central neurotropic activity and can be used in medical practice for preventive purposes in practically healthy individuals of various professions, including those requiring increased attention and coordination of movements (transport drivers, operators, etc.).

Drug interaction

When prescribed with other medications, no negative effects were observed.

Storage conditions and terms

Store at a temperature no higher than 25°C. Keep out of reach of children. Shelf life-2 years.

Arbidol
(Umifenovir)
Maximum
200mg
10
capsules

  • $16.00