Expiration date: 01/2025
Enromag ( Enromag) - for the treatment of animal diseases of bacterial and mycoplasma etiology.
STRUCTURE
Enromag in 1 ml as an active substance contains enrofloxacin-50 mg or 100 mg and excipients: butyl alcohol-30 mg, potassium hydroxide (to bring the pH) and water for injection-up to 1 ml.
PHARMACOLOGICAL PROPERTIES
Enromag belongs to the antibacterial drugs of the fluoroquinolone group. Enrofloxacin, which is part of the drug, is active against Gram-positive and gram-negative bacteria of the following species: E. coli, Haemophilus, Klebsiella, Pasteurella, Pseudomonas, Proteus, Bordetella, Brucella! Chlamydia, Enterobacter Campylobacter, Erysipeloids,. Corynebacterium 'Staphylococcus, Streptococcus, Actinobacillus, Clostridium, Bacteroides' Fusobacterium, and Mycoplasma.
The mechanism of bactericidal action of enrofloxacin is based on the ability to inhibit the activity of the enzyme gyrase, which ensures DNA replication in the bacterial cell.
When administered intramuscularly, enrofloxacin is rapidly absorbed into the blood and penetrates almost all organs and tissues, reaching a maximum concentration in 0.5-1 hour after administration.
The therapeutic concentration of enrofloxacin after a single injection remains in the body for 24 hours. Enrofloxacin is excreted from the body mainly in unchanged form and partially in the form of a metabolite-ciprofloxacin mainly in the urine.
Enromag by the degree of exposure to the body belongs to moderately dangerous substances (hazard class 3 according to GOST 12.1.007-76).
DOSAGE AND APPLICATION
Enromag is prescribed to large and small cattle, pigs, dogs, cats and rabbits for the treatment of bronchopneumonia, colibacteriosis, salmonellosis, pasteurellosis, mycoplasmosis and other diseases caused by microorganisms sensitive to fluoroquinolones, as well as for the treatment of atrophic rhinitis, enzootic pneumonia and mastitis-metritis-agalactia syndrome in pigs.
The drug is administered to animals subcutaneously (pigs - intramuscularly) once a day for 3-5 days.
Sows with mastitis-metritis-agalactia syndrome are given the drug within 1-2 days.
In connection with a possible pain reaction, you should not inject more than 5 ml of the drug in one place in large animals, and more than 2.5 ml in small animals.
SPECIAL INSTRUCTIONS
The features of the drug's action during its first use and cancellation were not revealed.
Skipping the next dose of the drug should be avoided, as this can lead to a decrease in therapeutic effectiveness. In case of missing one dose, the use of the drug is resumed as soon as possible in the same dosage and according to the same scheme.
Slaughter of pigs, large and small cattle for meat is allowed no earlier than 14 days after the last administration of the drug.
The meat of animals that are forced to be killed before the expiration of the specified period can be used after heat treatment for feeding fur-bearing animals.
CONTRAINDICATIONS
Contraindication to the use of Enromag is an increased individual sensitivity of the animal to fluoroquinolones (including in the anamnesis).
It is forbidden to use the drug in dairy animals, due to the release of enrofloxacin with milk.
It is not allowed to use Enromag with significant disorders of the development of cartilage tissue, lesions of the nervous system, accompanied by convulsions, to puppies and kittens before the end of their growth period, as well as to females during pregnancy and lactation.
SIDE EFFECTS
When using Enromag in accordance with this instruction, side effects and complications are usually not observed. In case of allergic reactions, the use of the drug is discontinued and antihistamines and symptomatic drugs are prescribed to the animal.
SHELF LIFE AND STORAGE
Store the drug in a closed packaging of the manufacturer in a dry place, protected from direct sunlight, separate from food and feed, at a temperature of 5°C to 25°C.
The shelf life of the medicinal product, subject to storage conditions, is 3 years from the date of production.
PACKAGING
Enromag is produced packaged in 20 ml glass bottles of the appropriate capacity, capped with rubber stoppers, reinforced with aluminum caps.
