Expiration date: 04/2025

Form release

Tablets

Packaging

In blister packs of 25 tablets. The package contains 2 blisters.

50 pieces

Pharmacological action

Vinpocetine-acre-a drug that improves cerebral circulation. It has a vasodilating, antihypoxic and antiplatelet effect. The mechanism of action is associated with the inhibition of phosphodiesterase, this leads to an increase in camp content in cells, which in turn causes a decrease in calcium content in the cytoplasm of smooth muscle cells and relaxation of myofibrils. 

Improves metabolism in tissues and dilates blood vessels of the brain, increases blood flow, mainly in ischemic areas, improves the supply of oxygen to the brain. Promotes glucose utilization and increases the level of catecholamines in the Central nervous system, stimulates the metabolism of norepinephrine and serotonin in brain tissues. Reduces platelet aggregation, blood viscosity, improves the deformability of red blood cells and normalization of venous outflow while reducing resistance of cerebral vessels. Systemic blood pressure decreases slightly. 

Vinpocetine is effective in acute stroke: accelerates regression of cerebral and focal neurological symptoms, improves memory, attention, intellectual productivity. In the elderly and senile age, the sensitivity of brain vessels to the relaxing effect of Vinpocetine increases, due to the sensitization of the adenylate cyclase-camp system in aging.

Indications

• Acute (if parenteral administration is impossible) and chronic forms of cerebral circulation insufficiency (including acute and residual stages of stroke, transient ischemic attacks, encephalopathy, dementia after cerebral circulation disorders. 
  
• Vascular diseases of the retina and / or choroid of the eye (due to atherosclerosis, angiospasm, thrombosis), degenerative changes of the macula caused by atherosclerosis or angiospasm, secondary glaucoma (due to obturation of vessels. 
  
• Age-related vascular or toxic (drug) hearing impairment, Meniere's disease, dizziness of labyrinthine origin. 
  
• Vegetative manifestations of climacteric syndrome.
  

Contraindications

• Severe cardiac arrhythmias. 
  
• CHD (heavy current). 
  
• In the acute stage of hemorrhagic stroke. 
  
• Pregnancy. 
  
• Lactation (breastfeeding). 
  
• Hypersensitivity to the drug.
  

Use during pregnancy and breast-feeding

Vinpocetine is contraindicated in pregnancy and lactation (breastfeeding).

Special instruction

In the application of Vinpocetine on the background of geparinoterapii increases the risk of hemorrhagic complications.

Composition

1 tablet contains: Vinpocetine 5 or 10 mg.

Excipients: lactose, low molecular weight cellulose, talc, magnesium stearate.

Method of application and doses

Vinpocetine should be prescribed 5-10 mg 3 times / day for 2 months. Before the abolition of the drug should gradually reduce the dose. Repeated courses 2-3 times a year are possible.

Drug interaction

In the application of Vinpocetine on the background of geparinoterapii increases the risk of hemorrhagic complications.

Overdose

Currently, cases of overdose of Vinpocetine have not been reported. 

Treatment: gastric lavage, activated charcoal, if necessary, symptomatic therapy.

Storage conditions

The drug should be stored in a dark place at a temperature of 15° to 35°C.

Shelf life

5 years.