Expiration date: 07/2025

The composition and form of issue 

Eye drops 0, 25%: 1 ml of solution contains 2. 5 mg of chloramphenicol, 

auxiliary substances: boric Acid, water for injection. 

5 or 10 ml in a dropper bottle.

Pharmacological action:

Levomycetin is a broad-spectrum antibiotic. The mechanism of antimicrobial action is associated with a violation of the synthesis of proteins of microorganisms. Acts bacteriostatically. Active against gram-positive (Staphylococcus spp., Streptococcus spp.) and gram-negative cocci (Neisseria gonorrhoeae, N. meningitidis), bacteria (Escherichia coli, Haemophilus influenza, Salmonella spp., Shigella spp., Klebsiella spp., Serratia spp., Yersinia spp., Proteus spp.), rickettsiae, spirochaetes, some large viruses. The drug is active against strains resistant to penicillin, streptomycin, sulfanilamidam. Resistance of microorganisms to chloramphenicol develops relatively slowly.

Indications

Bacterial eye infections caused by sensitive microflora: conjunctivitis, keratitis, blepharitis, blepharoconjunctivitis, keratoconjunctivitis, neuroparalytic keratitis in the presence of a secondary bacterial infection.

Method of application and doses

Locally, adults and children are buried in the conjunctival SAC 1 drop 3-4 times a day. The drug is used for no more than 10 days. Prolongation of a course of treatment is possible only by appointment of the doctor.

Side effect

Local allergic reactions.

With prolonged use: reticulocytopenia, leukopenia, granulocytopenia, thrombocytopenia, erythrocytopenia, aplastic anemia, agranulocytosis, secondary fungal infection.

Contraindications

  • Hypersensitivity to chloramphenicol, tiamfenikol, azidophenyl, 
  • inhibition of bone marrow hematopoiesis,  
  • acute intermittent porphyria,  
  • the deficit glukozo-6-fosfatdegidrogenaza,  
  • hepatic and/or renal failure,  
  • pregnancy, lactation. 

Caution: neonatal period (up to 4 weeks) and early childhood.

Special instruction:

With caution, patients who have previously received treatment with cytostatic drugs or radiation therapy are prescribed.

Storage conditions 

In a cool, dark place. Keep out of reach of children.

Shelf life 2 years.

After opening the bottle, use the solution for 30 days.

Levomycetin
0.25%
eye
drops